DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and Clic6

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_766057.1	Gene:	Clic6 / 209195	MGIID:	2146607	Length:	596	Species:	Mus musculus

Alignment Length:	208	Identity:	46/208 - (22%)
Similarity:	76/208 - (36%)	Gaps:	52/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQAGDHL-KPDMLRKNPQHTVPMLEDGESCIWDSHAIIGYLVNKYAQSDELYPKDPLKRAVVDQR 99
            :|.|:.| :.:..|:|.    |.||:|:.  ...|.|..::       ...|..:.:......||
Mouse   333 VQGGEELGRVNGRRENG----PALEEGDP--GQEHDITLFV-------KAGYDGESIGNCPFSQR 384

  Fly   100 LH---FETGVLFHGIFKQLQRALFKENATEVPKD--RLA------------ELKDAYALLEQFLA 147
            |.   :..||:|:.....|:|.         |.|  .||            |:|.....:|:||.
Mouse   385 LFMILWLKGVIFNVTTVDLKRK---------PADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLE 440

  Fly   148 ENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLSAWL--ARISALPFYEEDNLRGARLL 210
            |.  :..|:        ...:.|.|..........:.|.||::  .:..|...||::.||..:.|
Mouse   441 EK--LVPPR--------YPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYEKNLLRALKKL 495

  Fly   211 ADKIRSKLPKQFD 223
            ...:.|.||.:.|
Mouse   496 DSYLNSPLPDEID 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	37/180 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	11/41 (27%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	29/138 (21%)
Clic6	NP_766057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..360		9/32 (28%)
		PHA02664	<69..167	CDD:177447
		GST_N_CLIC	360..448	CDD:239359	22/113 (19%)
		O-ClC	363..596	CDD:129941	36/172 (21%)
		GST_C_CLIC6	455..594	CDD:198334	14/54 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930