DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and Gdap1

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_034397.1	Gene:	Gdap1 / 14545	MGIID:	1338002	Length:	358	Species:	Mus musculus

Alignment Length:	244	Identity:	56/244 - (22%)
Similarity:	101/244 - (41%)	Gaps:	44/244 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NLILYGTESSPPVRAVLLTLRALQLDHEFHTLDMQAGDHLKPDMLRKNPQHTVPMLEDGESCIWD 67
            :||||....|...:.|.|.:....|..|.|.:.:...:|.:|..:|.|....||:|..||:.|.:
Mouse    25 HLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGENIICE 89

  Fly    68 SHAIIGYLVNKYAQSDELYPKDPLKRAVVDQRLHFETGVLFHGIFKQLQRALFKENATEVPKDRL 132
            :..||.||...:.  ||..|           ||..:.|.::   :.::|.  ::|....:|
Mouse    90 ATQIIDYLEQTFL--DERTP-----------RLMPDEGSMY---YPRVQH--YRELLDSLP---- 132

  Fly   133 AELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLS--------AW 189
               .|||.        :..:..|:||: |..|.|..:|...|......::..||:        |:
Mouse   133 ---MDAYT--------HGCILHPELTV-DSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAY 185

  Fly   190 LARISAL--PFYEEDNLRGARLLADKIRSKLPKQFDKLWQKAFEDIKSG 236
            :|:...|  ...:.||::..:.:.|::...|.:...:|.::..|..:.|
Mouse   186 IAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEG 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	49/202 (24%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	24/72 (33%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	24/129 (19%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	23/71 (32%)
		GST_C_GDAP1	179..289	CDD:198336	10/56 (18%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844844
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840