DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf5 and Chit1

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001271454.1	Gene:	Chit1 / 71884	MGIID:	1919134	Length:	464	Species:	Mus musculus

Alignment Length:	437	Identity:	115/437 - (26%)
Similarity:	206/437 - (47%)	Gaps:	88/437 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDPSLTNDRQ 89
            :....||||:....|..|....:....:::|.|  |..:::.:||:|  .:::.:::   .||..
Mouse    18 WGSAAKLVCYLTNWSQYRTEAVRFFPRDVDPNL--CTHVIFAFAGMD--NHQLSTVE---HNDEL 75

  Fly    90 HYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQASVLAELNNNGFD 154
            .|:.:.:|:.|.|.::.||:|||       ....:.|:..::..:.:|::|..|.|:.|...|||
Mouse    76 LYQELNSLKTKNPKLKTLLAVGG-------WTFGTQKFTDMVATASNRQTFVKSALSFLRTQGFD 133

  Fly   155 GIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEEL----QSDLRRG 215
            |:||.|:||..|                   .|.:||      :|:|..|:::|    |.:.:..
Mouse   134 GLDLDWEFPGGR-------------------GSPTVD------KERFTALIQDLAKAFQEEAQSS 173

  Fly   216 G--QLLTVSMLPHVSAELFID----VPKVLSNVDFVNLGTYDFQTPERDPKVADLPTPLYAMYDR 274
            |  :||..:.:|  |....:|    |.|:..::||:||..|||.:...  |.....:|||.....
Mouse   174 GKERLLLTAAVP--SDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLE--KTTGHNSPLYKRQGE 234

  Fly   275 D---PSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNS--GITGYPPIPAANGAAPPG 334
            .   ...||...|..|:.:.:..|  ||.:|:.:|||::.:..:|  |: |.|    |.|...||
Mouse   235 SGAAAEQNVDAAVTLWLQKGTPAS--KLILGMPTYGRSFTLASSSDNGV-GAP----ATGPGAPG 292

  Fly   335 RQTVTPGLLSWPEICDLLQQ-QPQDREVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPL 398
            ..|...|:|::.|.|...:: :.:|::||              ||::  |:|     ||.::|..
Mouse   293 PYTKDKGVLAYYEACSWKERHRIEDQKVP--------------YAFQ--DNQ-----WVSFDDVE 336

  Fly   399 TAAIKAGFVHAQGLGGVAFHDLSMDDFRGQ-CAGEKFPILRSIKFKL 444
            :...||.::..:||||.....|.:|||:|. |....:|::|:::.:|
Mouse   337 SFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQGPYPLIRTLRQEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	114/430 (27%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	107/408 (26%)
Chit1	NP_001271454.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	113/429 (26%)
		Chitooligosaccharide binding. /evidence=ECO:0000250	70..71		0/3 (0%)
		Chitooligosaccharide binding. /evidence=ECO:0000250	97..100		2/9 (22%)
		Chitooligosaccharide binding. /evidence=ECO:0000250	210..213		0/2 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	385..416
		CBM_14	418..464	CDD:366726
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840