DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and Cht4

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	114/414 - (27%)
Similarity:	184/414 - (44%)	Gaps:	76/414 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGI-DAVTYKIKSLDPSLTND--RQHYR 92
            |.|::...:..|.|..:.:.::::|:|  |..:.|.:.|| ||..:  ||||..|..|  .....
  Fly    26 LNCYWGTWANYRPGDGKFTPSDIDPSL--CTHISYTFFGISDAGEF--KSLDTWLDMDDGLGFIS 86

  Fly    93 HITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQASVLAELNNNGFDGID 157
            ...||:::.|:::.|..|||    .:||   |.||..:......|.:|.::.||.:....|||:|
  Fly    87 QTIALKQRNPNLKILAVVGG----WNEG---STKYSAMAADPAKRATFVSTSLAFIQQYSFDGLD 144

  Fly   158 LAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEELQSDLRRGGQLLTVS 222
            |.|::|..|            |.             ||..||.|.|||.|::....:.|..|.::
  Fly   145 LDWEYPGQR------------GG-------------SEADRENFVTLLREIKETYDQYGLELGIA 184

  Fly   223 M-LPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPTPLYAMYDRDPSHNVQYQVQY 286
            : ....||.:..|:|.:..::.|:|:.||||..........:.|.|           .|...:.|
  Fly   185 VGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLP-----------EVAESIDY 238

  Fly   287 WMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDL 351
            |::..:  ...||.:|:..||.::.|:.:|  ..:|. .|..|....|..|...|.|.:.|||..
  Fly   239 WLSHGA--PAEKLILGIGFYGHSYQMSDSS--QNWPG-AACIGPGTAGVYTRENGFLGYHEICLN 298

  Fly   352 LQQQPQDREVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVA 416
            ..|...|:|      .|.|      ||:     ||:.  |:||::|.:..:|...|.::.|||..
  Fly   299 NWQTVFDQE------NGAP------YAF-----QGDQ--WIGYDNPESIQLKMQLVESRNLGGAM 344

  Fly   417 FHDLSMDDFRGQCAGEKFPILRSI 440
            ...:..|||||.| ||.:|:|:::
  Fly   345 MWSIETDDFRGLC-GESYPLLKTM 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	114/414 (28%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	104/395 (26%)
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	114/414 (28%)
		Glyco_18	28..351	CDD:214753	103/393 (26%)
		CBM_14	421..462	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463803
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840