DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and chit1

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001005792.1	Gene:	chit1 / 448265	XenbaseID:	XB-GENE-5801457	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	115/468 - (24%)
Similarity:	194/468 - (41%)	Gaps:	116/468 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMWIQKNPFLGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVY 65
            ::|      .||.|   |..|...:|.  ||||::...|..|..||:.....::|.|  |..|:|
Frog     5 LLW------AGLFL---LLHFHHGFAY--KLVCYFTNWSQYRPEPAKYMPGNIDPKL--CTHLIY 56

  Fly    66 GYAGIDAVTYKIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRL 130
            .:|     |.....:.|...||...|:...||:::.|::..||::||..       ..:.|:..:
Frog    57 AFA-----TMNSNKIAPYEWNDDVLYKQYNALKQQNPNLVTLLAIGGWN-------FGTQKFTEM 109

  Fly   131 LEQSEHRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSE 195
            :..:.:||.|..||:..|...||:||||.:::|.:|            ||             ..
Frog   110 VSSAGNRKIFIDSVIEYLRLYGFNGIDLDFEYPGSR------------GS-------------PP 149

  Fly   196 EHREQFATLLEEL------------QSDLRRGGQLLTVSMLPHVSA-----ELFIDVPKVLSNVD 243
            |.:.:|..|.:|:            ||.|     |:|.:    |||     :...::.::...:|
Frog   150 EDKHRFTILTQEMLKAFEDEAAATNQSRL-----LMTAA----VSAGKGTIDAGYEIAEIGKTLD 205

  Fly   244 FVNLGTYDFQTPERDPKVADLPTPLYAMYDRDPS----HNVQYQVQYWMNQTSEISVHKLHVGVT 304
            |:::.||||. ...|| |:...:|| ....:|..    .|::|.:.||  :.:.:...||.:|..
Frog   206 FISVMTYDFH-GGWDP-VSGHNSPL-CKGSKDTGDFQYFNIRYAMNYW--KDNGVPAQKLLIGFP 265

  Fly   305 SYGRAW-NMTRNSGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQQQP----QDREVPHL 364
            :|||.: |...::...|.|    .:||...|:.|...|..::.|||..|....    .|::||:.
Frog   266 TYGRTFRNPNPSNCDVGIP----VSGAGSAGQYTREAGFWAYYEICTWLSGTTINWIADQKVPYA 326

  Fly   365 RKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQ- 428
            .|..:                     |||:::..:...|..|:...|..|.....:.:|||.|.
Frog   327 CKGNE---------------------WVGFDNQDSYECKVKFLKESGFAGAMVWAIDLDDFSGTF 370

  Fly   429 CAGEKFPILRSIK 441
            |...|:|::..:|
Frog   371 CNQGKYPLISHLK 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	108/439 (25%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	100/418 (24%)
chit1	NP_001005792.1	GH18_chitolectin_chitotriosidase	24..386	CDD:119351	107/438 (24%)
chit1	NP_001005792.1	CBM_14	442..491	CDD:366726
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010