DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and chia.3

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_998378.1	Gene:	chia.3 / 406819	ZFINID:	ZDB-GENE-040426-2891	Length:	471	Species:	Danio rerio

Alignment Length:	458	Identity:	117/458 - (25%)
Similarity:	196/458 - (42%)	Gaps:	111/458 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGI---- 70
            |.|:|| .:||..       ::.|::...|..|.|..:.:.|.::|.|  |..|:|.::.|
Zfish    10 LSLVLC-HVAFSM-------EMACYFTNWSQYRPGIGKYTPANVDPYL--CTHLIYAFSIINQRN 64

  Fly    71 DAVTYKIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSE 135
            :.|||:        .||...|:....|:.|.|.::.||:|||..       ..|.::..::....
Zfish    65 ELVTYE--------WNDETLYKAFNELKNKNPTLKTLLAVGGWN-------FGSAQFSIMVSNPA 114

  Fly   136 HRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQ 200
            :||:|..|.:..|..:||||:||.|::|..|            ||             ..|.:::
Zfish   115 NRKTFIQSTIKFLRTHGFDGLDLDWEYPGAR------------GS-------------PPEDKQR 154

  Fly   201 FATLLEEL----QSDLRRGGQ---LLTVSMLPHVSA-----ELFIDVPKVLSNVDFVNLGTYDFQ 253
            |..|.:||    :::.:..|.   :||.:    |||     :...::.::...::|:|:.||||.
Zfish   155 FTLLCKELVAAYEAESKATGNPQLMLTAA----VSAGKGTIDDGYEIAEIAKYLNFINVMTYDFH 215

  Fly   254 -TPERDPKVADLPTPLYAMYDRDPS----HNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMT 313
             |.||   .....:||| ...:|..    .|..|.::||.:..:  .|.||.:|..:|||.:.:|
Zfish   216 GTWER---FTGHNSPLY-QGSKDEGDLIYFNTDYAMRYWRDNGT--PVEKLRMGFAAYGRTFRLT 274

  Fly   314 RNSGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQ----QQPQDREVPHLRKVGDPTKRF 374
            .:....|.|    |:|.|..|..|...|..|:.|||..|:    |...|::||:..|
Zfish   275 SSDTSVGAP----ASGPASAGTYTREAGFWSYYEICGFLEGTTIQWIDDQKVPYATK-------- 327

  Fly   375 GIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQ-CAGEKFPILR 438
                         |..|||::...:...|..::..:..||.....|.:|||.|| |:....|::.
Zfish   328 -------------NSEWVGFDTKESYETKVRYLKDKNFGGAFVWALDLDDFAGQFCSQGNHPLMA 379

  Fly   439 SIK 441
            .::
Zfish   380 HLR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	111/438 (25%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	104/417 (25%)
chia.3	NP_998378.1	Glyco_18	24..363	CDD:214753	104/415 (25%)
		GH18_chitolectin_chitotriosidase	25..385	CDD:119351	111/435 (26%)
		ChtBD2	421..469	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592081
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840