DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and Cht2

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	116/478 - (24%)
Similarity:	188/478 - (39%)	Gaps:	105/478 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 MWIQKNPFLGLLLCSFLAFFQSTYAEVGKL-----VCFYDAQSFVREGPAQMSLAELEPALQFCN 61
            :|:     |.||..:..:.:.|..|..|.|     ||:....:..|......::...:|.|  |.
  Fly    14 LWL-----LLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNL--CT 71

  Fly    62 FLVYGYAGIDAVTYKIKSLDPSLTNDRQH----YRHITALRKKYPHVRFLLSVGGDRDVNSEGVA 122
            .:||.:||:|.....||||||......::    |..:|.|::.:||::..|::||    .:||.|
  Fly    72 HVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGG----WNEGSA 132

  Fly   123 DSDKYLRLLEQSEHRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSS 187
            :   |..|:..:..|..|...|.:.:....|||:||.|::|..|
  Fly   133 N---YSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQR--------------------- 173

  Fly   188 SSVDEKSEEHREQFATLLEELQSDLRRGGQLLT--VSMLPHVSAELFIDVPKVLSNVDFVNLGTY 250
                :.....||.|..|.:||:.:....|.|||  :.....|..|.: ||.::...:|::::..|
  Fly   174 ----KGKPADRENFVLLTKELREEFDEHGLLLTSAIGASKKVIDEAY-DVRQISRYLDYLHIMCY 233

  Fly   251 DFQTPERDPKVADLPTPLYAMYDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRN 315
            |:. ...|.:|. ...||.|..| ||. :|::.:.|.:...:  ...||.:|:..|||.:. |..
  Fly   234 DYH-GSWDRRVG-YNAPLTAPAD-DPL-SVKFSIDYLLKLGA--PPEKLVMGLPFYGRTFK-TLA 291

  Fly   316 SGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQQQ---------PQDREVPHLRKVGDPT 371
            ||...    ..:.|....|..|...|.|.:.|||..|..|         ||..:|....:....|
  Fly   292 SGFLN----DVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFT 352

  Fly   372 KRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQC------- 429
            :...:               |.|:...:.|.|..|..::.|.||....:..|||.|.|
  Fly   353 QEINV---------------VTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTY 402

  Fly   430 ------------AGEKFPILRSI 440
                        :.:.:|:||:|
  Fly   403 EDFQKVTAAPKRSSQNYPLLRTI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	109/450 (24%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	100/412 (24%)
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	99/407 (24%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	108/444 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910