DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and chia.4

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_956740.1	Gene:	chia.4 / 337333	ZFINID:	ZDB-GENE-030131-9279	Length:	475	Species:	Danio rerio

Alignment Length:	452	Identity:	124/452 - (27%)
Similarity:	201/452 - (44%)	Gaps:	101/452 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GLLLCSFLAFFQSTYAEVG---KLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDA 72
            ||:   |||.......:.|   :|.|::...|..|....:...:.::|.|  |..|:|.::.|:
Zfish     3 GLI---FLAGISLALCQCGLASQLACYFANWSQYRPDVGKYMPSNVDPHL--CTHLIYAFSVIN- 61

  Fly    73 VTYKIKS-LDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEH 136
                ||: |..|..||...|:...||::..|:::.||:||   .:|    ..|.::.|::...:.
Zfish    62 ----IKNKLATSEWNDETLYQSFNALKQSNPNLKTLLAVG---TLN----LGSTQFSRMVSTPQK 115

  Fly   137 RKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQF 201
            |::|..|.:..|..:||||:||.|::|               ||          .|...|.:.:|
Zfish   116 RQTFIESSIKFLRTHGFDGLDLDWEYP---------------GS----------GESPPEDKHRF 155

  Fly   202 ATLLEEL----QSD---LRRGGQLLTVSMLPHVSAELFI-----DVPKVLSNVDFVNLGTYDFQT 254
            ..|.:||    |::   .||...:||.:    |:|...|     ::.:|...:||:|:.||||..
Zfish   156 TLLCKELLKAYQAESKATRRPRLMLTAA----VAARKGIIDAGYEIAEVSKYLDFINIMTYDFHG 216

  Fly   255 PERDPKVADLPTPLYAMYDRDPS----HNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRN 315
            ...:  |....:||| ...||..    :|..:.:.||.:|.:  .|.||.:|..:|||.:.::..
Zfish   217 SWEN--VTGHNSPLY-RDSRDTGDQIYYNTDFAMTYWRDQGA--PVEKLRMGFAAYGRTFCLSSA 276

  Fly   316 SGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQ----QQPQDREVPHLRKVGDPTKRFGI 376
            ....|.|    .:|.|..|..|...|..|:.|||..||    :|..|::||
Zfish   277 VNGLGAP----VSGPASAGTYTREAGYWSYYEICTFLQRASVEQIADQKVP-------------- 323

  Fly   377 YAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGE-KFPIL 437
            ||     .:|.|  |||::|..:...|..::..:|.||.....|.:|||.||..|: |:|::
Zfish   324 YA-----TEGLN--WVGFDDQKSYETKVDYLKEKGFGGAFVWSLDLDDFSGQFCGQGKYPLI 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	118/430 (27%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	110/413 (27%)
chia.4	NP_956740.1	Glyco_18	22..363	CDD:214753	110/413 (27%)
		GH18_chitolectin_chitotriosidase	25..381	CDD:119351	117/427 (27%)
		ChtBD2	425..473	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940