DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and Chit1

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	450	Identity:	123/450 - (27%)
Similarity:	217/450 - (48%)	Gaps:	88/450 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYK 76
            |.|..........:....||.|::...:..|.|.|:....:::|.|  |..::|.:||::  .::
  Rat     5 LALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNL--CTHVIYAFAGLN--NHQ 65

  Fly    77 IKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQ 141
            :.:::|   ||...|:.:.:|:|:.|.::.||:|||    .|.|   :.|:..::..:..|::|.
  Rat    66 VSTVEP---NDELFYQELNSLKKRNPKLKTLLAVGG----WSFG---TQKFTDMVATASTRQTFV 120

  Fly   142 ASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLE 206
            .|.|:.|..:||||:||.|::|.:|                   .|.:||      :|:|..|::
  Rat   121 NSALSFLRTHGFDGLDLDWEYPGSR-------------------GSPAVD------KERFTALIQ 160

  Fly   207 EL----QSDLRRGG--QLLTVSMLP----HVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKV 261
            :|    |.:.|..|  :||..:.:|    ||.|...:|  |::.::||:||..|||.:..  .|.
  Rat   161 DLAKAFQEEARASGKSRLLLTAAVPTGRGHVDAGYEVD--KIVQSLDFINLMAYDFHSSW--DKT 221

  Fly   262 ADLPTPLYAMY---DRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNM--TRNSGITGY 321
            ....:|||...   .:|...||...|..|:.:.:..|  ||.:|:.:|||::.:  :.:||: |.
  Rat   222 TGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTPAS--KLMLGMPAYGRSFTLASSSDSGV-GA 283

  Fly   322 PPIPAANGAAPPGRQTVTPGLLSWPEICDLL-QQQPQDREVPHLRKVGDPTKRFGIYAYRAADDQ 385
            |    |.|...||..|...|:|.:.|:|... :|:.:|::||::                   .|
  Rat   284 P----ATGPGAPGPYTKEKGILVYFEVCSWKGKQRIEDQKVPYV-------------------SQ 325

  Fly   386 GENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQ-CAGEKFPILRSIKFKL 444
            |..  |||::|..:...||.:|..:||||.....|..|||:|. |...::|::|::..:|
  Rat   326 GNQ--WVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	120/430 (28%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	113/408 (28%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	119/429 (28%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350396
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940