Protein Alignment Idgf5 and Chi3l1

DIOPT Version :10

• Sequence 1: NP_611321.3
• Gene: Idgf5 / 37104
• FlyBaseID: FBgn0064237
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_031721.2
• Gene: Chi3l1 / 12654
• MGIID: 1340899
• Length: 389
• Species: Mus musculus
• Alignment Length: 443
• Identity: 125/443 - (28%)
• Similarity: 197/443 - (44%)
• Gaps: 97/443 - (21%)

  Fly    18 LAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDP 82
            |...||..|.  ||||::.:.|..|||........::|.|  |..::|.:|.|        |.|.
Mouse    21 LMLLQSCSAY--KLVCYFTSWSQYREGVGSFLPDAIQPFL--CTHIIYSFANI--------SSDN 73

  Fly    83 SLT----NDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQAS 143
            .|:    ||..:|..:..|:.:..:::.||||||.:       ....::..:...:|.|.:|..|
Mouse    74 MLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWK-------FGEKRFSEIASNTERRTAFVRS 131

  Fly   144 VLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEEL 208
            |...|.:.||||:||||.:|:.|.|                              :.|:||::||
Mouse   132 VAPFLRSYGFDGLDLAWLYPRLRDK------------------------------QYFSTLIKEL 166

  Fly   209 QSDLRRGGQ------LLTVSM-LPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPT 266
            .::..:..|      ||:.:: ...|:.:...|:.::..::||:||.||||....|  ::....:
Mouse   167 NAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWR--QITGHHS 229

  Fly   267 PLY-----AMYDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPA 326
            ||:     ..:||  ..||.|.|||.:...::.|  ||.:|:.::|:::.:..:....|.|
Mouse   230 PLFQGQKDTRFDR--YSNVNYAVQYMIRLGAQAS--KLLMGIPTFGKSFTLASSENQLGAP---- 286

  Fly   327 ANGAAPPGRQTVTPGLLSWPEICDLLQQQPQDREVPHL--RKVGDPTKRFGIYAYRAADDQGENG 389
            .:|...|||.|...|.|::.||||.|    :..||..|  .||...||               ..
Mouse   287 ISGEGLPGRFTKEAGTLAYYEICDFL----KGAEVHRLSNEKVPFATK---------------GN 332

  Fly   390 LWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQC-AGEKFPILRSIK 441
            .||||||..:...|.||:..:.|.|.....|.:|||:|.| ..|.||:..:||
Mouse   333 QWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	121/431 (28%)
Chi3l1	NP_031721.2	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	120/430 (28%)
		Important for AKT1 activation and IL8 production	333..347		6/13 (46%)