DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf5 and Chia

DIOPT Version :9

Sequence 1:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_997469.1	Gene:	Chia / 113901	RGDID:	1303058	Length:	473	Species:	Rattus norvegicus

Alignment Length:	428	Identity:	107/428 - (25%)
Similarity:	188/428 - (43%)	Gaps:	86/428 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDPSLTNDRQHYRHIT 95
            |||::...:..|.|.......::.|.|  |..|:|.:||:.  ..:|.:::   .||...|:...
  Rat    24 LVCYFTNWAQYRPGLGSFKPDDINPCL--CTHLIYAFAGMQ--NNQITTIE---WNDVTLYKAFN 81

  Fly    96 ALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQASVLAELNNNGFDGIDLAW 160
            .|:.:...::.||::||    .:.|.|   .:..::..|::|::|..||:..|...||||:||.|
  Rat    82 DLKNRNSKLKTLLAIGG----WNFGTA---PFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDW 139

  Fly   161 QFPKNR--PKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEELQSDLRRGGQLLTVSM 223
            ::|.:|  |...:.:|..:...||..|...::    |.:|.:.                ::|.::
  Rat   140 EYPGSRGSPPQDKHLFTVLVKELREAFEQEAI----ESNRPRL----------------MVTAAV 184

  Fly   224 LPHVS-AELFIDVPKVLSNVDFVNLGTYDFQ------TPERDPKVADLPTPLYAMYDRDPSH--- 278
            ...:| .:...::|::...:||:::.|||..      |.|.        :|||.:.....|:
  Rat   185 AAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGEN--------SPLYKLPTETGSNAYL 241

  Fly   279 NVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGAAPPGRQTVTPGLL 343
            ||.|.:.||.:..:  ...||.||...||..:.:: |...||.....:.||  |.|..|...|..
  Rat   242 NVDYVMNYWKDNGA--PAEKLIVGFPEYGHTYILS-NPSDTGIGAPTSGNG--PAGPYTRQAGFW 301

  Fly   344 SWPEICDLLQQ-QPQD----REVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIK 403
            ::.|||..|:. ..||    :|||              |||:..:       ||||::..:.::|
  Rat   302 AYYEICTFLRNGATQDWDAPQEVP--------------YAYKGNE-------WVGYDNIKSFSVK 345

  Fly   404 AGFVHAQGLGGVAFHDLSMDDFRGQ-CAGEKFPILRSI 440
            |.::.....||.....:.:|||.|. |...|||:..::
  Rat   346 AQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	107/428 (25%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	99/408 (24%)
Chia	NP_997469.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	107/428 (25%)
		Glyco_18	24..365	CDD:214753	99/408 (24%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	70..71		0/3 (0%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	97..100		2/6 (33%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	210..213		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	395..421
		ChtBD2	426..473	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840