DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fj and Fjx1

DIOPT Version :9

Sequence 1:	NP_477483.1	Gene:	fj / 37089	FlyBaseID:	FBgn0000658	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001102425.1	Gene:	Fjx1 / 366140	RGDID:	1306113	Length:	449	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	155/503 - (30%)
Similarity:	223/503 - (44%)	Gaps:	90/503 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 AAFVFGMALGVVVPMFG--LPRHQDSPPDLPEEQIQMVAVEPLSSYRVEFIKETDELSAEQVFRN 146
            ||.::.:|||.::.::|  ||...:.|...|.|                     |.|....:...
  Rat    10 AAGLWLLALGSLLTLWGGLLPPRTELPASRPPE---------------------DRLPRHPIQSG 53

  Fly   147 AFHLEQDKDAPDSMVVKKLDTNDGSIKEFHVQRTASGRYRKGPERRLSKKMPERVQPQETSRSPT 211
            ....|.....|..:|   .|...||:|.|....|.:......|.|          .|.:..|...
  Rat    54 GPAPEPRFPLPPPLV---WDARGGSLKTFRALLTLAAGADNPPGR----------HPDDRGRHVP 105

  Fly   212 TSPTNPTSEHQAGFIEEDVYWGPTVEQALPKGFAAKDQVSWERFVGEQGRVVRLEQ-GCGRMQNR 275
            :..:.| :||.|  :...|:|...:|:.:|:||:.....:|.. |....|||.|:: ||||..||
  Rat   106 SGLSWP-AEHTA--VHGGVFWSRGLEEQVPRGFSEAQAAAWLE-VARGARVVALDRGGCGRSSNR 166

  Fly   276 MVVFADGTRACARYRQNTDQIQGEIFSYYLGQLLNIS-NLAPSAATVVDTSTPNWAAALGDITQA 339
            :..||||||||.||..|.:|||||..||||.:||.:. ::.|.|...|:.....|.....::..|
  Rat   167 LARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWVQVQEELRTA 231

  Fly   340 QWKERRPVVLTRWLSDLEPAGIPQPFQPLERHLNKHDVWNLTRHMQSERQAQSQPHGLLKRLGAA 404
            .|.|...|.|||||.:|....:|:|             |      :||       .|.|:.|..|
  Rat   232 HWTEGSVVSLTRWLPNLTDVVVPEP-------------W------RSE-------DGRLRPLRDA 270

  Fly   405 SSPGSAHQSNAIEETGTGTETANGALVQRLIELAQWSDLIVFDYLIANLDRVVNNLYNFQWNADI 469
                             |.|..|.:..: |::|.||:|||:||||.||.||:|:||::.||:..:
  Rat   271 -----------------GGELTNLSQAE-LVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRV 317

  Fly   470 MAAPAHNLARQSASQLLVFLDNESGLLHGYRLLKKYEAYHSLLLDNLCVFRRPTIDALRRL-RAA 533
            |.....||.| .....|||||||:||:||||:...::.|:..||.::||||..|...:..| |..
  Rat   318 MHRATSNLHR-GPGGALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQ 381

  Fly   534 GAGRRLRDLFERTTSAGVRDVLPSLPDKSVKILVERIDRVLGQVQKCQ 581
            .|..||..|:.|.......  |..|.|...::|..|:|.:...:..|:
  Rat   382 DAAARLLRLYSRHEPRFPE--LAELADPHAQLLQRRLDFLAKHILHCK 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fj	NP_477483.1	Four-jointed-like_C	255..583	CDD:198459	118/330 (36%)
Fjx1	NP_001102425.1	Four-jointed-like_C	145..429	CDD:198459	118/331 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349369
Domainoid	1	1.000	189	1.000	Domainoid score	I3194
eggNOG	1	0.900	-	-		E1_28N0C
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7717
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3799
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1414662at2759
OrthoFinder	1	1.000	-	-		FOG0007373
OrthoInspector	1	1.000	-	-		oto98378
orthoMCL	1	0.900	-	-		OOG6_110463
Panther	1	1.100	-	-	LDO	PTHR13147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5496
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.760