DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and si:dkey-206f10.1

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_009293230.1	Gene:	si:dkey-206f10.1 / 560719	ZFINID:	ZDB-GENE-041014-154	Length:	1187	Species:	Danio rerio

Alignment Length:	284	Identity:	93/284 - (32%)
Similarity:	149/284 - (52%)	Gaps:	36/284 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 GIAILVVVLIVSPVIIVLV--KNAAATIQ---LYALNLSQKAKELKREKRKSDSLLFQMLPPSVA 476
            |::||::.:.   :|.||.  :...||.:   |:.|...|:.:|::..:..::.||..:||..||
Zfish   854 GVSILLMAMF---MIAVLYNGRRWEATTRLDFLWRLQAQQEVQEMRDLREHNECLLHNILPAHVA 915

  Fly   477 MQL----KQTQQVPAELYEAVTIYFSDIVGFT------EIAADCTPLEVVTFLNSIYRVFDERIE 531
            ...    :..|::.::.|:.|.:.|:.|.||.      ||..:  .:|.:..||.|...|||.:|
Zfish   916 RHFLERNRNDQELYSQSYDEVGVMFASIAGFNDYYEQKEIKHE--GVECLKLLNEIIADFDELLE 978

  Fly   532 ---CYDVYKVETIGDSYMVASGLP------VKNGNKHISEIATMALDLLDASSVFRIPRAGDEFV 587
               ..|:.|::|||..||.||||.      |.|...|:||:...||.:.:  ::..|.:......
Zfish   979 ESYFLDIEKIKTIGSCYMAASGLSPDKQSRVVNDWHHLSELVLFALAMQE--TLREINKHSMNNF 1041

  Fly   588 QIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEH 652
            |:|.|:..||||||::|...|:|.::|.|||.||||:|||.:.:|.:.|...:.|.. .||..|.
Zfish  1042 QLRVGIAHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGVSGRIQVPEATRNILAD-WGFVLEL 1105

  Fly   653 RGLIDVKG----KGLMSTYWLTCK 672
            ||.|.:||    ||.:.||:::.|
Zfish  1106 RGEIYIKGVSERKGRVRTYFISTK 1129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	12/42 (29%)
		CYCc	459..647	CDD:214485	68/206 (33%)
		Guanylate_cyc	485..669	CDD:278633	73/202 (36%)
si:dkey-206f10.1	XP_009293230.1	AC_N	<135..380	CDD:292831
		CYCc	343..538	CDD:214485
		Guanylate_cyc	382..564	CDD:278633
		DUF1053	<611..661	CDD:283888
		CYCc	899..1097	CDD:214485	67/201 (33%)
		Guanylate_cyc	928..1126	CDD:278633	73/202 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810