Protein Alignment CG33958 and npr1a

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001038402.1
• Gene: npr1a / 560653
• ZFINID: ZDB-GENE-060503-539
• Length: 1067
• Species: Danio rerio
• Alignment Length: 749
• Identity: 228/749 - (30%)
• Similarity: 343/749 - (45%)
• Gaps: 140/749 - (18%)

  Fly     2 LNGKAHKSGENPDPSPCPAGGSRM-------PTPSVKIDISTCQSNRPMESRTAPDDVNPSGEGG 59
            ||....:||..|   |......||       .|..|::|     .|...|...|..|:..:..|.
Zfish   369 LNDTMDRSGSRP---PGDVVNKRMWNRTYHGVTGLVQLD-----ENGDREIDFALWDMTDTKTGD 425

  Fly    60 LLLVPTHHNLQLDKIS--------VRSISSEDISNGGSGRCCNAAARNPAIKTGRRLQLMQMIIL 116
            ..:|..::..|...|.        ::.....||..      |.....|||. ..:.:.:.|||.:
Zfish   426 YQIVSVYNGSQKQMILEPGMKVHWLKGRPPPDIPE------CGFKNDNPAC-LAKTVTMHQMISI 483

  Fly   117 PFIPILALIVQTSVTLQEILEYRSAVADIETQVTIA------TDLGKVVTRLQLERSEVAFYIFT 175
            ....|..:||..:|.:...|:       :|.::|..      .|:....|...|.|:.....|..
Zfish   484 VVCFIFIIIVTVTVFIYRKLK-------LENELTAQLWRVHWEDIQMSNTEKVLRRACSKLTISL 541

  Fly   176 NGSKQRANLTLR-----FANTDHALNNMTTWSEISVPTAPDEDEDDREMMLNRYEFQSRLNEFRD 235
            .||...:.||:.     :|.|.:...|:|....::    ....|..|:::......:...||...
Zfish   542 RGSNYGSLLTMDGNFQIYAKTGYYKGNITAIKYVN----KKRIELTRKVLFELKHMRDVQNEHLT 602

  Fly   236 R---VRLEPEESSI-TEVMNWYTSINRGLLHHLSEQIKETDNSGV---W--RYLVGFKNLLKSIE 291
            |   ..::|....| ||.      ..||.|..|.|      :.|:   |  ||     :|:..|
Zfish   603 RFIGACIDPPNICILTEY------CPRGSLQDLME------SEGITLDWMFRY-----SLINDI- 649

  Fly   292 CQNIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQ 356
            .:.:|..........|:|.:.|.|...|:       :....:|.....:..:|:.....|: |:|
Zfish   650 VKGMAFLHNSVIVSHGNLKSSNCVVDSRF-------VLKITDYGLESFHKDSNLDDVHAFY-ARQ 706

  Fly   357 MGTT--LLK--NNPNVSNERSAIEYYELMNNYTDDLRIL-------------QKALRRLIK---E 401
            :.|.  ||:  |.|....::..:..:.::   ..:|.:|             ::.:.|:::   .
Zfish   707 LWTAPELLRADNPPACGTQKGDVYSFGII---LQELALLKGVFYLEGPCLSPKEIIERVVEGRWP 768

  Fly   402 YVDKTLVEADRKEAIGIAIL---------------VVVLI-------VSPVIIVLVKNAAATIQL 444
            |:...|......|.:|..:|               :.||:       .|.::    .|..:.::.
Zfish   769 YLRPLLCPQSHSEEMGQLMLRCWSEDVNERPDFSQIKVLLRKNNCGYGSNIL----DNLLSRMEQ 829

  Fly   445 YALNLSQKAKE----LKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTE 505
            ||.||.:..:|    ...||||:::||:|:||.|||.|||:.:.|.||.:::||||||||||||.
Zfish   830 YANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQLKRGEMVQAEAFDSVTIYFSDIVGFTA 894

  Fly   506 IAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDL 570
            ::|:.||:||||.||.:|..||..|:.:||||||||||:|||.|||||:||..|..|||.|:|.|
Zfish   895 LSAESTPMEVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLAL 959

  Fly   571 LDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHIT 635
            |:|...|||....:..:::|.|:|:|||.||:||.||||||||||||||||||||.|||.|||::
Zfish   960 LEAVHSFRIRHRPNLQLRLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVS 1024

  Fly   636 EEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWL 669
            |.....||:...|:.|.||.:::||||.|.||||
Zfish  1025 EATRAVLQEFNCFQLELRGDVEMKGKGRMRTYWL 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453	50/267 (19%)
		CYCc	459..647	CDD:214485	114/187 (61%)
npr1a	NP_001038402.1	PBP1_NPR_A	48..449	CDD:380608	19/87 (22%)
		PK_GC-A_B	540..814	CDD:270944	54/306 (18%)
		HNOBA	<820..868	CDD:462234	18/51 (35%)
		CYCc	847..1032	CDD:214485	112/184 (61%)