Protein Alignment CG33958 and adcy1a

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001161821.1
• Gene: adcy1a / 557026
• ZFINID: ZDB-GENE-070705-302
• Length: 1114
• Species: Danio rerio
• Alignment Length: 573
• Identity: 140/573 - (24%)
• Similarity: 248/573 - (43%)
• Gaps: 107/573 - (18%)

  Fly   166 RSEVAF-YIFT--NGSKQRANLTLRFANTDHALNNMTTWSEISVPTAPDEDEDDREMMLNRYEFQ 227
            ::|:.| .:.|  :..|:||   ||.|:  ..|.|.|::|...|..:|.       ..:|||  .
Zfish   512 KAEIPFSNVMTCEDDDKRRA---LRTAS--EKLRNRTSFSAGMVQNSPG-------TRVNRY--I 562

  Fly   228 SRLNEFRDRVRLEPEESSITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKN-LLKSIE 291
            .||.|.|   :.|.|.:.:..:...|.|..|       ||          |||..:.: .:.::.
Zfish   563 GRLIEAR---QTESEMADLNYITLTYRSRER-------EQ----------RYLQVYDDAFISAVV 607

  Fly   292 CQNIATS-FGIRYY---GRGSLTAENFVSYVRYEFMAREMINST--------------------- 331
            ...:.|| |.:.|:   .:|.|.....|..:.:...:...::.|
Zfish   608 ISLVLTSFFAVVYFLIIPQGLLVVILLVLCLCFHMASVMYLHVTHVQCSPDCLTLQIRTVLCGFL 672

  Fly   332 --LNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYELMNNYTDDLRI---- 390
              |.|:.....:.|.:..:.:.:.:..|.|.:..|...|.........|..::.....|.:
Zfish   673 VLLMYSVTQGCVVTCVPWSLEGNSSISMVTVVTVNGTGVGYRVCKYTPYVFLSCVMASLSVALYL 737

  Fly   391 ----LQKALRRLIKEYVDKTLVE-ADRKEAIGIAI--------LVVVLIVSPVIIVLVKNAAATI 442
                |.|.|..|:...:...::| :..::|:|...        ::.:|:.|..:::..:.....:
Zfish   738 RVSSLPKILLLLLLNILHTVVMETSGYRKAVGGGFFHTHGYDPVLAMLLFSGALVLHCRQLDLKL 802

  Fly   443 Q---LYALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQL----KQTQQVPAELYEAVTIYFSDI 500
            :   |:|....::..:::|.|..:..:||.:||..||...    .:...:..:.|..|.:.|:.|
Zfish   803 RLDYLWATQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLLSNPRNMDLYYQSYSQVGVLFASI 867

  Fly   501 VGFT----EIAADCTPLEVVTFLNSIYRVFDERI--ECY-DVYKVETIGDSYMVASGLPVKNGNK 558
            ..|.    |:..:...:|.:..||.|...||..:  ||| |:.|::|||.:||.|.||....|:|
Zfish   868 PNFNDFYIELDGNNMGVECLRLLNEIIADFDALMDKECYRDIEKIKTIGSTYMAAVGLVPTEGSK 932

  Fly   559 -------HISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDT 616
                   |:..:|..|:::.|....... ::.::|| :|.|::.||||||::|.:.|:|.::|:|
Zfish   933 VKKSISAHLCTVADYAIEMFDVLDAINY-QSYNDFV-LRVGINVGPVVAGVIGARRPQYDIWGNT 995

  Fly   617 VNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWL 669
            ||.||||:|||...||.:||::...|.  |.:....||.:.|||||.|.||:|
Zfish   996 VNVASRMDSTGVQGKIQVTEDVFRLLS--GYYDFNCRGQVSVKGKGQMLTYFL 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	51/268 (19%)
		HNOBA	<439..479	CDD:285003	10/42 (24%)
		CYCc	459..647	CDD:214485	67/205 (33%)
		Guanylate_cyc	485..669	CDD:278633	71/197 (36%)
adcy1a	NP_001161821.1	AC_N	<154..285	CDD:292831
		CYCc	251..446	CDD:214485
		Guanylate_cyc	287..469	CDD:278633
		DUF1053	513..601	CDD:283888	32/121 (26%)
		CYCc	819..1029	CDD:214485	69/213 (32%)
		Guanylate_cyc	852..1048	CDD:278633	72/199 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810