Protein Alignment CG33958 and Gucy1a1

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_058786.2
• Gene: Gucy1a1 / 497757
• RGDID: 68436
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 635
• Identity: 173/635 - (27%)
• Similarity: 264/635 - (41%)
• Gaps: 136/635 - (21%)

  Fly    94 NAAARNPAIKTGR-RLQLMQM------IILPFIPILALIVQTSVTLQEILEYRSAVADIETQVTI 151
            ||...:|..||.| |:.|..:      :|.|....|.|.:|.::...:|.|.|::....:.:..|
  Rat    53 NAEGSHPQRKTSRNRVYLHTLAESIGKLIFPEFERLNLALQRTLAKHKIKENRNSSEKEDLERII 117

  Fly   152 ATD---LGKVVTRLQLERSEVAFYIFTNGSKQRANL---TLR-FANTDHALNNMTTWSEISVPTA 209
            |.:   .|..|..|:....|..|.|.....:....:   ||: |.|:...|...::..:.:....
  Rat   118 AEEAIAAGVPVEALKDSLGEELFKICYEEDEHILGVVGGTLKDFLNSFSTLLKQSSHCQEAERRG 182

  Fly   210 PDED------EDDREMMLNRYEFQSR----------------LNEFRDRVRLEPE--ESSITEVM 250
            ..||      :.|::.:...|.|..|                |.|....|.|.|.  .|..||.:
  Rat   183 RLEDASILCLDKDQDFLNVYYFFPKRTTALLLPGIIKAAARILYESHVEVSLMPPCFRSECTEFV 247

  Fly   251 NWYTSINRGLLHHLSEQIKETDNS----GVWRYLVGFKNLLKSIECQNIATSF------------ 299
            |     ...||:  |..:|.|..|    .....||    :..|:.|:.....|
  Rat   248 N-----QPYLLY--SVHVKSTKPSLSPGKPQSSLV----IPTSLFCKTFPFHFMLDRDLAILQLG 301

  Fly   300 -GIR-------YYGRGSLTAENFVSYVRYEFMAREMINSTLNYAPMLKNM--------YTNITST 348
             |||       :.|:     .||..:  :|.:..: ||.|.:....:.||        :.|:  .
  Rat   302 NGIRRLVNKRDFQGK-----PNFEEF--FEILTPK-INQTFSGIMTMLNMQFVIRVRRWDNL--V 356

  Fly   349 KKFHRAKQM----------GTTLLKNNPNVSNERSAIEYYELMNNYTDDLRILQKALRRLIKEYV 403
            ||..|...:          ...|...:|.|..    :|.:.....|..|:.| ..|||
  Rat   357 KKSSRVMDLKGQMIYIVESSAILFLGSPCVDR----LEDFTGRGLYLSDIPI-HNALR------- 409

  Fly   404 DKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQKAKELKREKRKSDSLLF 468
            |..|:....:...|:                 |.....::   ..|....:.|:.||:|:..||.
  Rat   410 DVVLIGEQARAQDGL-----------------KKRLGKLK---ATLEHAHQALEEEKKKTVDLLC 454

  Fly   469 QMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECY 533
            .:.|..||.||.|.|.|.|:.:..||:.||||||||.|.:.|:||:|:|.||::|..||::....
  Rat   455 SIFPSEVAQQLWQGQIVQAKKFNEVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGEL 519

  Fly   534 DVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPV 598
            ||||||||||:|.||.||. :..:.|..:||.|||.:::.|:....|..  |.:::|.|:|:|.|
  Rat   520 DVYKVETIGDAYCVAGGLH-RESDTHAVQIALMALKMMELSNEVMSPHG--EPIKMRIGLHSGSV 581

  Fly   599 VAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGF 648
            .||:||.|||||||||:.|..|::.||....:||:::...:..|:...||
  Rat   582 FAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGF 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	60/306 (20%)
		HNOBA	<439..479	CDD:285003	10/39 (26%)
		CYCc	459..647	CDD:214485	84/187 (45%)
		Guanylate_cyc	485..669	CDD:278633	74/164 (45%)
Gucy1a1	NP_058786.2	HNOB	<111..234	CDD:285002	22/122 (18%)
		HNOBA	276..465	CDD:285003	43/230 (19%)
		CYCc	444..633	CDD:214485	86/191 (45%)
		Guanylate_cyc	471..642	CDD:278633	74/164 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820