Protein Alignment CG33958 and Adcy1

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_033752.1
• Gene: Adcy1 / 432530
• MGIID: 99677
• Length: 1118
• Species: Mus musculus
• Alignment Length: 270
• Identity: 83/270 - (30%)
• Similarity: 145/270 - (53%)
• Gaps: 24/270 - (8%)

  Fly   421 LVVVLIVSPVIIVLVKNAAATIQ---LYALNLSQKAKELKREKRKSDSLLFQMLPPSVA----MQ 478
            ::.:|:.|..:.:..:.....::   |:|....::..:::|.|..:..:||.:||..||    |.
Mouse   787 IMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMS 851

  Fly   479 LKQTQQVPAELYEAVTIYFSDIVGFT----EIAADCTPLEVVTFLNSIYRVFDERIE---CYDVY 536
            ..:...:..:.|..|.:.|:.|..|.    |:..:...:|.:..||.|...|||.::   ..|:.
Mouse   852 NPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLE 916

  Fly   537 KVETIGDSYMVASGLPVKNGNK-------HISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVH 594
            |::|||.:||.|.||....|.:       |:..:|..|:|:.|....... ::.::|| :|.|::
Mouse   917 KIKTIGSTYMAAVGLAPTAGTRAKKSISSHLCTLADFAIDMFDVLDEINY-QSYNDFV-LRVGIN 979

  Fly   595 TGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVK 659
            .||||||::|.:.|:|.::|:|||.||||:|||...:|.:|||:|..|::. .::...||.:.||
Mouse   980 VGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKRC-SYQFVCRGKVSVK 1043

  Fly   660 GKGLMSTYWL 669
            |||.|.||:|
Mouse  1044 GKGEMLTYFL 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453
		CYCc	459..647	CDD:214485	67/205 (33%)
Adcy1	NP_033752.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		AcyC	99..455	CDD:441717
		Guanylate_cyc	293..475	CDD:425528
		Interaction with calmodulin. /evidence=ECO:0000250	492..519
		Guanylate_cyc	858..1055	CDD:425528	70/199 (35%)
		Interaction with calmodulin. /evidence=ECO:0000250	1023..1046		7/23 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1079..1118