DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33958 and Gyc89Db

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	144/537 - (26%)
Similarity:	242/537 - (45%)	Gaps:	109/537 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 LRFANTDH---ALNNMTTWSEISVPTAPDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSIT 247
            |.|.|.|:   .:|.:...|::.:|:.      |..:.|..:.|...|:... ::.|..|:.
  Fly   194 LDFDNRDYMAKRVNVIAHPSQLKMPSV------DLNVFLELFPFTIVLDHDM-KITLAGEKI--- 248

  Fly   248 EVMNWYTSINRGLLH------------HLSEQIK---ETDNSGVWRYLVGFKNLLKSIECQNIAT 297
             |..|       :||            |:.|:.|   ..|....|..::..:.:|...|.
  Fly   249 -VETW-------ILHNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLFEFEL----- 300

  Fly   298 SFGIRYYGRGSLTAENFVSY---VRYEFMAREMIN--STLNYAPMLKNMYTNITSTKKF------ 351
               ||       |..|..:|   :.::|   |..:  |:||.|..:.     :.|.|:|
  Fly   301 ---IR-------TGHNRAAYDAALNFDF---ENFDEASSLNEAQAMA-----LASAKEFSAENAK 347

  Fly   352 HRAKQMGTTLLKNNPNVSNERSAIEYYELMNNYTDDLR-ILQKALRRLIKE-----YVDKTLVEA 410
            ..|....|:..:.:|.....|.::           .|| ||.|.....||:     ::...|:|
  Fly   348 EEAAAAATSKDEIDPATGQRRHSV-----------GLRSILLKGQMFYIKDVDSLIFLCSPLIE- 400

  Fly   411 DRKEAIGIAILVVVLI---VSPVIIVLVKNAAATIQLYALNLSQKAKELKRE-------KRKSDS 465
            :..|..||.:.:..|.   :|..:::......:.:::......|::.||::.       ||:.|.
  Fly   401 NLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDE 465

  Fly   466 LLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAAD--CTPLEVVTFLNSIYRVFDE 528
            ||:.|:|..:|.:::::::...:.:|.|::.|.:::...:..::  ...::.||.||.::...||
  Fly   466 LLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDE 530

  Fly   529 RIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGV 593
            .|....||||||:|..||..||.|..| ..|......:||.::.......:|.     |.||.|:
  Fly   531 EIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMKKVKAHALPG-----VAIRVGI 589

  Fly   594 HTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDV 658
            ::||||||:||.|:||||||||||||||||||:.:...|.::......:|:| |::.|.||.:.|
  Fly   590 NSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKV-GYKVEARGFVKV 653

  Fly   659 KGKGLMSTYWLTCKDGP 675
            ||||.|.||||.  :||
  Fly   654 KGKGEMETYWLL--EGP 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	47/239 (20%)
		HNOBA	<439..479	CDD:285003	11/46 (24%)
		CYCc	459..647	CDD:214485	69/196 (35%)
		Guanylate_cyc	485..669	CDD:278633	73/185 (39%)
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	61/313 (19%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	74/183 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820