DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33958 and Gyc88E

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_001036711.1	Gene:	Gyc88E / 41825	FlyBaseID:	FBgn0038295	Length:	1097	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	177/531 - (33%)
Similarity:	263/531 - (49%)	Gaps:	112/531 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 YTSINRGLLHHLSEQIKETDNSGVWRYL----VGFKNLLKSIECQNIATSFGIRYYGRG------ 307
            |.|..||.:::...||:|     |.||.    :..:.:.:.|....:..:|.:.:..|.
  Fly   133 YRSKRRGFVYYTMGQIRE-----VARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASL 192

  Fly   308 SLTAEN----FVSYVRYE-----------FMAREMINSTLNYAPMLKNMYTNITS---------T 348
            ::|.|.    ..::|.:|           .:.|.:.||.:...|.|  :...||:         .
  Fly   193 AMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPEL--LGKKITAWFDLVRPLIA 255

  Fly   349 KKFHRAKQMGTTLLKNNPNV--------SNERSAIEYYELMNNYTDDLRILQKALR---RLIKEY 402
            .||.       |:|....|:        ..||..::..:|:.:  :|....:|:||   :::  |
  Fly   256 FKFQ-------TILNRTNNIFELVTVDPVTERFDVQNEDLLQH--EDGSEPEKSLRLKGQMV--Y 309

  Fly   403 VDK--------TLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLS-----QKAK 454
            ::.        |.|..|....|...:.:..|.:......|:  .|.|.|...|.|:     ||:|
  Fly   310 MENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLM--LAGTQQSVELKLALDQEQQKSK 372

  Fly   455 ELK-------REKRKSDSLLFQMLPPSVAMQLKQTQQV--PAELYEAVTIYFSDIVGFTEIAADC 510
            :|:       .|.|::|.||:||:|..||.:|::.:..  ..|::::|:|.|||||.||||.:..
  Fly   373 KLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRI 437

  Fly   511 TPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASS 575
            ||:|||:.||::|.:||:..|...|||||||||:|||.:|.|.|:.| |...:..||||::||.:
  Fly   438 TPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDAN-HAERVCDMALDMVDAIT 501

  Fly   576 VFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHD 640
            ..:.|..| :.::||.|||:|.|||||||.|||||||||||||||||||||..|.|:||:|   .
  Fly   502 DLKDPSTG-QHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISE---S 562

  Fly   641 SLQQVG-GFRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAREEISWRADIQPVFLDHLKLH----- 699
            :...:| .::...||.|||||||.|.||||          ||...|..:|  ....|::|
  Fly   563 TKVLIGPNYKIIERGEIDVKGKGTMGTYWL----------EERENRLPLQ--LTAALQVHPLSPV 615

  Fly   700 PPTDYKLPKRK 710
            |||  ..||.|
  Fly   616 PPT--PTPKTK 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	34/184 (18%)
		HNOBA	<439..479	CDD:285003	19/51 (37%)
		CYCc	459..647	CDD:214485	99/190 (52%)
		Guanylate_cyc	485..669	CDD:278633	100/186 (54%)
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	10/35 (29%)
		HNOBA	201..404	CDD:311573	47/217 (22%)
		CYCc	383..571	CDD:214485	99/192 (52%)
		Herpes_ICP4_C	794..>955	CDD:332854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820