DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and rut

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_511156.2	Gene:	rut / 32406	FlyBaseID:	FBgn0003301	Length:	2248	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	124/466 - (26%)
Similarity:	197/466 - (42%)	Gaps:	103/466 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 NIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMG 358
            :|:.||.:|                    ||..:....|.|:....|::|.::.    |.....|
  Fly   761 DISESFSLR--------------------MAITIFTVILIYSVGQVNVFTCVSD----HPCSGNG 801

  Fly   359 TTLLKNNPNVSNERSAIEYYELMN------NYTDDLR--ILQKALRRL----------------I 399
            ||..:|:   |:.:.::..|..::      :.:..||  |:.|:|..|                |
  Fly   802 TTSFQND---SHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNI 863

  Fly   400 KEYVDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQKAKELKREKRKSD 464
            .|..|..:..:.....|.:|.:.:.:|...|...||:..|....|:.|..||:.||:...:..:.
  Fly   864 FECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNK 928

  Fly   465 SLLFQMLPPSVA-----MQLKQTQQVPAELYEAVTIYFSDIVGF----TEIAADCTPLEVVTFLN 520
            .:|..:||..||     .|.:...::..:.|..|.:.|:.:..|    ||:......||.:..||
  Fly   929 RILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLN 993

  Fly   521 SIYRVFDERIE---CYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRA 582
            .|...|||.::   ...:.|::|:|.:||...||           |....:...|.:||.|...|
  Fly   994 EIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGL-----------IPEYKIQPNDPNSVRRHMTA 1047

  Fly   583 GDEFVQ------------------IRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEA 629
            ..|:|:                  :|.|::.||||||::|.:.|:|.::|:|||.||||:|||..
  Fly  1048 LIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVP 1112

  Fly   630 QKIHITEEMHDSLQQVGG-FRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAREEISWRADIQPVFL 693
            ....:|:|:.|||  ||. |....||.|.|||||.|.||:| |..|      ..|...:::....
  Fly  1113 GYSQVTQEVVDSL--VGSHFEFRCRGTIKVKGKGDMVTYFL-CDSG------NKSLNGEVRNAMS 1168

  Fly   694 DHLKLHPPTDY 704
            ....||.| ||
  Fly  1169 LPQSLHAP-DY 1178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	21/109 (19%)
		HNOBA	<439..479	CDD:285003	12/44 (27%)
		CYCc	459..647	CDD:214485	63/217 (29%)
		Guanylate_cyc	485..669	CDD:278633	70/209 (33%)
rut	NP_511156.2	AC_N	<17..255	CDD:292831
		CYCc	230..425	CDD:214485
		Guanylate_cyc	266..438	CDD:278633
		DUF1053	624..696	CDD:283888
		SLC5-6-like_sbd	<742..>893	CDD:294310	29/158 (18%)
		CYCc	924..1134	CDD:214485	65/222 (29%)
		Guanylate_cyc	954..1151	CDD:278633	70/209 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810