DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33958 and GUCY2F

DIOPT Version :9

Sequence 1:NP_001033958.1 Gene:CG33958 / 37088 FlyBaseID:FBgn0053958 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_001513.2 Gene:GUCY2F / 2986 HGNCID:4691 Length:1108 Species:Homo sapiens


Alignment Length:481 Identity:159/481 - (33%)
Similarity:231/481 - (48%) Gaps:103/481 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   231 NEFRDRVRLEPEESSITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNI 295
            |:..:.:||..||||:.|:: |..                             ..||::.....:
Human   692 NDILEMLRLSEEESSMEELL-WTA-----------------------------PELLRAPRGSRL 726

  Fly   296 ATSFGIRYYGRGSLTAENFV---SYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQM 357
            . ||....|....:..|..|   .:...:..|:|:||......|:.:                  
Human   727 G-SFAGDVYSFAIIMQEVMVRGTPFCMMDLPAQEIINRLKKPPPVYR------------------ 772

  Fly   358 GTTLLKNNPNVSNERSAIEYYELMNNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAIGIAILV 422
                    |.|..|.:..|..:||.....:....:.....:..::  ||..:..:..        
Human   773 --------PVVPPEHAPPECLQLMKQCWAEAAEQRPTFDEIFNQF--KTFNKGKKTN-------- 819

  Fly   423 VVLIVSPVIIVLVKNAAATIQLYALNLS----QKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQ 483
                       ::.:....::.|:.||.    ::.:||:.||:|::.||.||||||||..||:..
Human   820 -----------IIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGC 873

  Fly   484 QVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVA 548
            .|..|.::.||:|||||||||.|:|...|:|||..||.:|.:||..|..:||||||||||:||||
Human   874 TVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVA 938

  Fly   549 SGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLF 613
            ||||.:||::|.:|||.|:||:|.:...|::....:..|:||.|:|:||||||:||..|||||||
Human   939 SGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLF 1003

  Fly   614 GDTVNTASRMESTGEAQKIHITEEMHDSLQQVG-GFRTEHRGLIDVKGKGLMSTYWLTCKDGPVR 677
            ||||||||||||||...:||::......||.:. |:..|.||..::||||...|:||..|.|   
Human  1004 GDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLIGKKG--- 1065

  Fly   678 AREEISWRADIQPVFLDHLKLHPPTD 703
                          |:..|.:.||.|
Human  1066 --------------FMKPLPVPPPVD 1077

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33958NP_001033958.1 NIT 159..396 CDD:285564 27/167 (16%)
HNOBA <439..479 CDD:285003 18/43 (42%)
CYCc 459..647 CDD:214485 107/188 (57%)
Guanylate_cyc 485..669 CDD:278633 101/184 (55%)
GUCY2FNP_001513.2 PBP1_sensory_GC_DEF_like 54..435 CDD:107366
ANF_receptor 75..412 CDD:279440
PKc_like 545..815 CDD:304357 29/181 (16%)
HNOBA <824..869 CDD:285003 18/44 (41%)
CYCc 848..1040 CDD:214485 108/191 (57%)
Guanylate_cyc 875..1062 CDD:278633 103/186 (55%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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