Protein Alignment CG33958 and Gucy2c

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_037302.1
• Gene: Gucy2c / 25711
• RGDID: 2771
• Length: 1072
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 187/587 - (31%)
• Similarity: 253/587 - (43%)
• Gaps: 133/587 - (22%)

  Fly   182 ANLTLRFANTDHALNNMTTWSEI-SVPTAPDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESS 245
            |.|.||....||.| ....||.| |....|.|..:...:.|       ::::.|.|       .:
  Rat   449 ALLVLRKYRRDHEL-RQKKWSHIPSENIFPLETNETNHVSL-------KIDDDRRR-------DT 498

  Fly   246 ITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFG---------- 300
            |..|........:.:|    :.:|..|.:...:..:....||:| :..|:...:|
  Rat   499 IQRVRQCKYDKKKVIL----KDLKHCDGNFSEKQKIELNKLLQS-DYYNLTKFYGTVKLDTRIFG 558

  Fly   301 -IRYYGRGSL--TAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLL 362
             :.|..||||  ...:.:||....||..|...|.||  .:.|.|       ...|.:|......|
  Rat   559 VVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLN--DIAKGM-------SYLHSSKIEVHGRL 614

  Fly   363 KNNPNVSNERSAIEYYELMNN-------------------------------------------- 383
            |:...|.:.|..::..:...|
  Rat   615 KSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQATISQKGDVYSFSIIAQEIILRKETF 679

  Fly   384 YTDDLRILQKALRRLIKEY------VDKTLVEADRKEAIGIAILVVVLIV--------------S 428
            ||...|...:.:.|:...|      .|..|..||.||      |.|.|:|              .
  Rat   680 YTLSCRDQNEKIFRVENSYGTKPFRPDLFLETADEKE------LEVYLLVKSCWEEDPEKRPDFK 738

  Fly   429 PVIIVLVK---------------NAAATIQLYALNLSQKAKE----LKREKRKSDSLLFQMLPPS 474
            .:...|.|               .....:|||:.||....:|    .|.|:.::|.|.|.:||..
  Rat   739 KIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRL 803

  Fly   475 VAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVE 539
            |...||:...|..||||.||||||||||||.|....||:|||..||.||:.||:.::.:||||||
  Rat   804 VVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVE 868

  Fly   540 TIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVG 604
            ||||:|:||||||::|||:|..:|:.||||:|.....|.:.......|.||.|||:||..||:||
  Rat   869 TIGDAYVVASGLPMRNGNRHAVDISKMALDILSFMGTFELEHLPGLPVWIRIGVHSGPCAAGVVG 933

  Fly   605 TKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVG-GFRTEHRGLIDVKGKGLMSTYW 668
            .||||||||||||||||||||||...:||::......|::.. .|..|.||...:||:|..:|||
  Rat   934 IKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTIAILRRTDCQFLYEVRGETYLKGRGTETTYW 998

  Fly   669 LT 670
            ||
  Rat   999 LT 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	51/271 (19%)
		HNOBA	<439..479	CDD:285003	14/43 (33%)
		CYCc	459..647	CDD:214485	103/188 (55%)
		Guanylate_cyc	485..669	CDD:278633	103/184 (56%)
Gucy2c	NP_037302.1	Periplasmic_Binding_Protein_Type_1	34..414	CDD:299141
		PKc_like	479..749	CDD:304357	53/303 (17%)
		STYKc	501..744	CDD:214568	46/262 (18%)
		CYCc	787..978	CDD:214485	103/190 (54%)
		Guanylate_cyc	814..1001	CDD:278633	106/187 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810