Protein Alignment CG33958 and Gucy1b2

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001257640.1
• Gene: Gucy1b2 / 25206
• RGDID: 2770
• Length: 742
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 140/378 - (37%)
• Similarity: 202/378 - (53%)
• Gaps: 71/378 - (18%)

  Fly   351 FH-------RAKQMGTTLLKNNPNVSNERSAI-EYYELMN-NYTDDLRILQKALRRLIKEYVDKT 406
            ||       |.||.|..:.|..|.:..::.|: ||:.::: ..|.::..:.|.:.   .::|.||
  Rat   275 FHIVFDEALRVKQAGVNIQKYVPGILTQKFALDEYFSIIHPQVTFNISSICKFIN---SQFVLKT 336

  Fly   407 LVEADRKEAIGIA------------------ILVVVLIVSPV----------------------- 430
                 |||.:..|                  :..::.:.||.
  Rat   337 -----RKEMMPKARKSQPMLKLRGQMIWMESLRCMIFMCSPKLRSLQELEESKMHLSDIAPHDTT 396

  Fly   431 --IIVLVKNAAATIQLYALNLSQKAKELK-------REKRKSDSLLFQMLPPSVAMQLKQTQQVP 486
              :|:|.:...|.::| :..|.:|.:||:       .||:|:::||:.|||..||.|||:.::|.
  Rat   397 RDLILLNQQRLAEMEL-SCQLEKKKEELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGRKVA 460

  Fly   487 AELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGL 551
            |..:|..||.|||:|.||.|.|.|.|:::|..|||:|..||.....:||||||||||:|||..|:
  Rat   461 AGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTSVHDVYKVETIGDAYMVVGGV 525

  Fly   552 PVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDT 616
            ||. ...|...:|..||.:..::.....|..| |.:|||.|:|||||:||:||.|||||||||||
  Rat   526 PVP-VESHAQRVANFALGMRISAKEVMNPVTG-EPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDT 588

  Fly   617 VNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWL 669
            |||||||||.|...|:|::...|.:|:. .||....||.|:|||||.|:||:|
  Rat   589 VNTASRMESHGLPSKVHLSPTAHRALKN-KGFEIVRRGEIEVKGKGKMTTYFL 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	13/53 (25%)
		HNOBA	<439..479	CDD:285003	16/46 (35%)
		CYCc	459..647	CDD:214485	96/187 (51%)
		Guanylate_cyc	485..669	CDD:278633	96/183 (52%)
Gucy1b2	NP_001257640.1	HNOB	2..163	CDD:285002
		HNOBA	267..453	CDD:285003	40/186 (22%)
		CYCc	432..622	CDD:214485	98/192 (51%)
		Guanylate_cyc	459..642	CDD:278633	97/185 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820