Protein Alignment CG33958 and Gucy1b1

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_036901.2
• Gene: Gucy1b1 / 25202
• RGDID: 2769
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 169/617 - (27%)
• Similarity: 263/617 - (42%)
• Gaps: 170/617 - (27%)

  Fly    89 SGRCCNAAARNPAIKTGRRLQL--------MQMIILPFIPILALIVQTSVTLQEILEYRSAVADI 145
            |.||.:|       :.|:.|.|        :|.|::..|..:|..:..:....::::.||...|
  Rat   119 SFRCTDA-------EKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRSEECD- 175

  Fly   146 ETQVTIATDLGKVVTRLQLERSEVAFYIFTNGSKQRANLTLRFANTDHALNNMTTWSEISVPT-- 208
            .||..|.          :.|..|..||                .:.|....|.|..|.||..|
  Rat   176 HTQFLIE----------EKESKEEDFY----------------EDLDRFEENGTQDSRISPYTFC 214

  Fly   209 --APDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEVMNW---YTSIN-RGLLHHLSEQ 267
              .|.....||::::.    |.....:|...:|:|.:.|:..|.:.   :..|: .|:|.|::..
  Rat   215 KAFPFHIIFDRDLVVT----QCGNAIYRVLPQLQPGKCSLLSVFSLVRPHIDISFHGILSHINTV 275

  Fly   268 IKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMINSTL 332
            .       |.|...|..::.| :||::..|.            ||  :|.:|   :..:||
  Rat   276 F-------VLRSKEGLLDVEK-LECEDELTG------------AE--ISCLR---LKGQMI---- 311

  Fly   333 NYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSN----ERSAIEYYEL-MNNYTDDLRILQ 392
             |.|                   :..:.|...:|:|.|    .|..:...:: :::.|.||.:|.
  Rat   312 -YLP-------------------EADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLG 356

  Fly   393 KALRRLIKEY--VDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQKAKE 455
            :..|   :||  ..:..:..||                                  |.|:.:|
  Rat   357 EQFR---EEYKLTQELEILTDR----------------------------------LQLTLRA-- 382

  Fly   456 LKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCT-------PL 513
            |:.||:|:|:||:.:||||||.:|:..:.|||:.|:.|||.||.||||.   |.|:       .:
  Rat   383 LEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFN---AFCSKHASGEGAM 444

  Fly   514 EVVTFLNSIYRVFDERIECYD---VYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASS 575
            ::|..||.:|..||...:...   ||||||:||.||..|||| :....|...|..:|||:::.:.
  Rat   445 KIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLP-EPCIHHARSICHLALDMMEIAG 508

  Fly   576 VFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHD 640
            ..::   ..|.|||..|:|||.||.|::|.:||||||||:|||..||.|:|||..||:::|..:.
  Rat   509 QVQV---DGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYR 570

  Fly   641 SLQQVGG----FRTEHRGLIDVKGKGLMSTYW 668
            .|.....    |..||||.:.:|||......|
  Rat   571 CLMSPENSDPQFHLEHRGPVSMKGKKEPMQVW 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	48/249 (19%)
		HNOBA	<439..479	CDD:285003	16/39 (41%)
		CYCc	459..647	CDD:214485	86/197 (44%)
		Guanylate_cyc	485..669	CDD:278633	82/198 (41%)
Gucy1b1	NP_036901.2	HNOB	2..166	CDD:285002	11/53 (21%)
		HNOBA	207..406	CDD:285003	61/290 (21%)
		CYCc	385..584	CDD:214485	87/205 (42%)
		Guanylate_cyc	412..605	CDD:278633	82/198 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820