DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and Gucy2f

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_001007577.1	Gene:	Gucy2f / 245650	MGIID:	105119	Length:	1108	Species:	Mus musculus

Alignment Length:	246	Identity:	124/246 - (50%)
Similarity:	169/246 - (68%)	Gaps:	5/246 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 LVKNAAATIQLYALNLS----QKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVT 494
            ::.:....::.|:.||.    ::.:||:.||:|::.||.||||.|||..||:...|..|.::.||
Mouse   820 IIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEPEGFDLVT 884

  Fly   495 IYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKH 559
            :|||||||||.|:|...|:|||..||.:|.:||..|..:||||||||||:||||||||.:||::|
Mouse   885 LYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRH 949

  Fly   560 ISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRME 624
            .:|||.|:||:|.:...|::....:..|:||.|:|:||||||:||..||||||||||||||||||
Mouse   950 AAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRME 1014

  Fly   625 STGEAQKIHITEEMHDSLQQVG-GFRTEHRGLIDVKGKGLMSTYWLTCKDG 674
            |||...:||::......||.:. |:..|.||..::||||...|:||..|.|
Mouse  1015 STGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLVGKKG 1065

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	17/43 (40%)
		CYCc	459..647	CDD:214485	106/188 (56%)
		Guanylate_cyc	485..669	CDD:278633	101/184 (55%)
Gucy2f	NP_001007577.1	PBP1_sensory_GC_DEF-like	54..435	CDD:380594
		PKc_like	545..815	CDD:419665
		HNOBA	<824..869	CDD:400168	17/44 (39%)
		CYCc	848..1040	CDD:214485	107/191 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810