Protein Alignment CG33958 and Gucy1b2

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_011243363.2
• Gene: Gucy1b2 / 239134
• MGIID: 2660873
• Length: 829
• Species: Mus musculus
• Alignment Length: 378
• Identity: 138/378 - (36%)
• Similarity: 201/378 - (53%)
• Gaps: 71/378 - (18%)

  Fly   351 FH-------RAKQMGTTLLKNNPNVSNERSAI-EYYELMN-NYTDDLRILQKALRRLIKEYVDKT 406
            ||       |.||.|..:.|..|.:..::..: ||:.::: ..|.::..:.|.:.   .:::.||
Mouse   388 FHVVFDEALRVKQAGVNIQKYVPGILTQKFGLDEYFSIVHPQVTFNISSICKFIN---SQFILKT 449

  Fly   407 LVEADRKEAIGIA------------------ILVVVLIVSPV----------------------- 430
                 |:|.:..|                  :..:|.:.||.
Mouse   450 -----RREMMPEAWKSQPTLKLRGQMIWMESLKCMVFMCSPKLRSLQELEESKMHLSDIAPHDTT 509

  Fly   431 --IIVLVKNAAATIQLYALNLSQKAKELK-------REKRKSDSLLFQMLPPSVAMQLKQTQQVP 486
              :|:|.:...|.::| :..|.:|.:||:       .||:|:::||:.|||..||.|||:.::|.
Mouse   510 RDLILLNQQRLAEMEL-SCQLEKKKEELRVLSNHLAIEKKKTETLLYAMLPEHVANQLKEGKKVA 573

  Fly   487 AELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGL 551
            |..:|..||.|||:|.||.|.|.|.|:::|..|||:|..||.....:||||||||||:|||..|:
Mouse   574 AGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHDVYKVETIGDAYMVVGGV 638

  Fly   552 PVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDT 616
            ||. ...|...:|..||.:..::.....|..| |.:|||.|:|||||:||:||.|||||||||||
Mouse   639 PVP-VESHAQRVANFALGMRISAKEVMNPVTG-EPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDT 701

  Fly   617 VNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWL 669
            |||||||||.|...|:|::...|.:|:. .||....||.|:|||||.|:||:|
Mouse   702 VNTASRMESHGLPNKVHLSPTAHRALEN-KGFEIVTRGEIEVKGKGKMTTYFL 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	12/53 (23%)
		HNOBA	<439..479	CDD:285003	16/46 (35%)
		CYCc	459..647	CDD:214485	96/187 (51%)
		Guanylate_cyc	485..669	CDD:278633	96/183 (52%)
Gucy1b2	XP_011243363.2	HNOB	115..276	CDD:400167
		HNOBA	380..566	CDD:400168	38/186 (20%)
		Guanylate_cyc	572..754	CDD:306677	97/185 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820