Protein Alignment CG33958 and Npr2

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_776149.1
• Gene: Npr2 / 230103
• MGIID: 97372
• Length: 1047
• Species: Mus musculus
• Alignment Length: 668
• Identity: 210/668 - (31%)
• Similarity: 304/668 - (45%)
• Gaps: 198/668 - (29%)

  Fly   117 PFIPILALIVQTSVT-----LQEILEYRSAVADIETQVTIATDLGKVVTRLQLERSEVAFYIFTN 176
            |...:..:.:.|.||     :...|.:|        ::.:..:|..::.|::.|..:     |.|
Mouse   452 PLSTLAIVALGTGVTFIMFGVSSFLIFR--------KLMLEKELASMLWRIRWEELQ-----FGN 503

  Fly   177 ------GSKQRANLTLR----------------FANTDHALNNMTTWSEISVPTAPDEDEDDREM 219
                  |:..|..|:||                ||||.|...|:.....::    ....|..|::
Mouse   504 SDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVN----KKRIELTRQV 564

  Fly   220 MLN-------RYEFQSR-------------LNEFRDRVRLEP--EESSITEVMNW---YTSIN-- 257
            :..       ::...:|             :.|:..|..|:.  |..||.  ::|   |:.||
Mouse   565 LFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSIN--LDWMFRYSLINDL 627

  Fly   258 -RGL--LHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRY--YGRGSL--TAENFV 315
             :|:  ||          ||     ::.....|||..|. :.:.|.::.  ||..|.  |||...
Mouse   628 VKGMAFLH----------NS-----IISSHGSLKSSNCV-VDSRFVLKITDYGLASFRSTAEPDD 676

  Fly   316 SYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTT--LLKNNPNVSNERSAIEYY 378
            |:..|                                 ||::.|.  ||..||..:......:.|
Mouse   677 SHALY---------------------------------AKKLWTAPELLSGNPLPTTGMQKADVY 708

  Fly   379 E---------LMNN--YTDDL-----RILQK---ALRRLIKEYVDKTLVEAD------------- 411
            .         |.:.  |.:.|     .|:||   ..|...:..:|:|.:..:
Mouse   709 SFAIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDP 773

  Fly   412 ----------------RKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQKAKELKR-- 458
                            .||. |.:||              .|....::.||.||.:..:|..:
Mouse   774 TERPDFGQIKGFIRRFNKEG-GTSIL--------------DNLLLRMEQYANNLEKLVEERTQAY 823

  Fly   459 --EKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNS 521
              ||||:::||:|:||.|||.|||:.:.|.||.:::||||||||||||.::|:.||::|||.||.
Mouse   824 LEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLND 888

  Fly   522 IYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEF 586
            :|..||..|:.:||||||||||:|||.||||.:||.:|..|||.|||.||||.|.|||.....:.
Mouse   889 LYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQ 953

  Fly   587 VQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTE 651
            :::|.|||||||.||:||.||||||||||||||||||||.|:|.|||::....|:|.::|.|:.|
Mouse   954 LRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLE 1018

  Fly   652 HRGLIDVKGKGLMSTYWL 669
            .||.:::||||.|.||||
Mouse  1019 LRGDVEMKGKGKMRTYWL 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453	60/313 (19%)
		CYCc	459..647	CDD:214485	115/187 (61%)
Npr2	NP_776149.1	PBP1_NPR_B	26..421	CDD:380607
		PK_GC-A_B	518..792	CDD:270944	56/328 (17%)
		HNOBA	<798..846	CDD:462234	19/61 (31%)
		CYCc	825..1009	CDD:214485	114/183 (62%)