Protein Alignment CG33958 and gcy-34

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 145/597 - (24%)
• Similarity: 256/597 - (42%)
• Gaps: 139/597 - (23%)

  Fly   201 WSEISVPTAPD-----EDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEVMNWYTSINRGL 260
            |.|:....:|:     ::.|.....::...:::.|.....|....|:.   |.:::::|. ..||
 Worm    83 WDELVRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPSFRCEENPDG---TLMLHYFTG-RPGL 143

  Fly   261 LHHLSEQIKETDN-----------SGVWRYLVGFKN----------LLKSIE------------- 291
            .|.:...:||...           .|..:..|...|          |:|::|
 Worm   144 YHIVKGVVKEVAKLVFNLDISLVVQGRTQRSVHMNNGERVEEHVIFLIKNVEEPRRDSDTSTTSA 208

  Fly   292 CQNIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQ 356
            ..::...||........::.::|...:.|.|    :::.:.........:|.:|.     :...|
 Worm   209 LTSVEPDFGEIIDDNLKVSLQDFSRALPYHF----VLDESCRLVQCGDELYNHIP-----NELLQ 264

  Fly   357 MGTTLLK----NNPNVSNERSAIEYYELMNNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAI- 416
            .||.:|:    |.|.:..:      :|.:.|:.:.:.:||.....|.|:::: .:.:.:|::.:
 Worm   265 PGTPILRIFEINRPQIPLD------FENICNFINAVFVLQVKTSPLRKKHMN-AMTKEEREQEVE 322

  Fly   417 --------------------GIAILV-----VVLIVSPVI------------------------- 431
                                |..:::     ::.:.||.:
 Worm   323 AMEEEVESNELTQGCHLKLKGQMMMLSTKKHIIYLCSPYVTSINELMQFGMRLTAMPLHDATRDL 387

  Fly   432 IVL----VKNAAATIQLYALN--LSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQV-PAEL 489
            |:|    :.:....:||.|.|  |.....||:.|::|:||:|..|||..:|.||...:.: |.|
 Worm   388 ILLNQQRLSDVEVNLQLEANNEQLETMTHELEVERQKTDSILKDMLPRKIAKQLLSGEHLEPCE- 451

  Fly   490 YEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVK 554
            ||| |:.|.|:..|.:|...|.|..:|..||.::...|..:....||||||:.||||..||:| .
 Worm   452 YEA-TVMFCDLPAFQQIIPVCQPKNIVKLLNEVFFKLDRIVVLRGVYKVETVSDSYMTVSGIP-D 514

  Fly   555 NGNKHISEIATMALDLL-DASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVN 618
            ..::|...:..:||.:: :|.||.. |.....|: :|.|:|:|.::||:||||||||||||:||.
 Worm   515 YTSEHAENMCHVALGMMWEARSVMD-PVNKTPFL-LRIGLHSGTIIAGVVGTKMPRYCLFGETVT 577

  Fly   619 TASRMESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAREEIS 683
            .||:|||.|.|.||..:...:....:.|.|....||.|:|||:|.:.||:|      :|:.::..
 Worm   578 LASQMESLGVAGKIQCSSWTYSKAMETGRFEFSPRGRINVKGRGDVETYFL------MRSLKKSI 636

  Fly   684 WRADIQPVFLDH 695
            |.      ..||
 Worm   637 WE------ITDH 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	37/237 (16%)
		HNOBA	<439..479	CDD:285003	16/41 (39%)
		CYCc	459..647	CDD:214485	77/189 (41%)
		Guanylate_cyc	485..669	CDD:278633	77/185 (42%)
gcy-34	NP_506319.1	HNOB	3..167	CDD:285002	14/87 (16%)
		HNOBA	224..441	CDD:285003	39/232 (17%)
		CYCc	421..609	CDD:214485	79/192 (41%)
		Guanylate_cyc	453..629	CDD:278633	75/185 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820