Protein Alignment CG33958 and gcy-31

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001024889.1
• Gene: gcy-31 / 191655
• WormBaseID: WBGene00001551
• Length: 702
• Species: Caenorhabditis elegans
• Alignment Length: 637
• Identity: 167/637 - (26%)
• Similarity: 265/637 - (41%)
• Gaps: 195/637 - (30%)

  Fly   199 TTWSEISVPTAPDED--EDDR-----------------------EMMLN----------RYEFQ- 227
            :||||:...:...:|  :.|:                       |:|.|          ::||.
 Worm    20 STWSEVKFVSGVTDDTFQMDKKFSEGLSHKLIWACHDVTGDPVDELMTNIGTSFYKFLTKFEFNK 84

  Fly   228 -------------SRLNEFRDRVR-----LEP-----EESSITEVMNWYTSINRGLLHHLSEQIK 269
                         :.|:...:.:|     |:|     |..|.|.:...|.|..||.||::..||:
 Worm    85 VLRVLGRTFPQFLNGLDNLHEYLRFTFPKLKPPSFYCEHESRTGLTLHYRSKRRGFLHYVQGQIR 149

  Fly   270 ET-------------------------------DNSGVWRYLVGFKNLLKSIECQNIATSFGIRY 303
            ..                               :|....|....::||..|| .:.:..:..|.:
 Worm   150 NISQELFQTEVVIELLDIEHDLNLEHVIMRLHFNNLDFNRQGTAYRNLNDSI-LEKVKITSDIFF 213

  Fly   304 --------YGRGSLTAENFVSYVRYEFMA---REMINST-LNYAPMLK-----------NMYTNI 345
                    :.||.......:..:|  .||   .:.||.| |...|.::           |::..|
 Worm   214 DIFPFIIVFNRGMRIRNIGIGLLR--VMAGIVGKKINQTFLLMRPFIRFRWEEIMLHSNNIFELI 276

  Fly   346 TS---------------------TKKFHRAKQMGTTLLKNNPNVSNERSAIEYYE---------- 379
            :|                     |::.||   ||....:...::..:...:|.:|
 Worm   277 SSDPIQEDEDGILVYKTTDVDQMTEERHR---MGDGEREKFLSLKGQMFYMEEWESICFVGIPVM 338

  Fly   380 --LMNNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATI 442
              |...|...|.|...||....::     ||.|..:::..:.:|            |.:.|..
 Worm   339 SHLPQMYKSGLFINDFALHDSSRD-----LVLASTQQSAELKLL------------LHQEAQK-- 384

  Fly   443 QLYALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPA--ELYEAVTIYFSDIVGFTE 505
               :.|:.:....||:|:|::|.||:||||.|||.||:..:...|  |.:::|||.|:|||.||:
 Worm   385 ---SRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFTDIVEFTK 446

  Fly   506 IAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDL 570
            :.:..|||||:.||..||..||:.|:.:.|||||||||:|||.||.|.|  .:|.:|.      :
 Worm   447 MCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTK--TEHDAEF------I 503

  Fly   571 LDASSVFRIPRAGD--------EFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTG 627
            ||.:|.|.: .||.        ..:.||.|||:|.||||:||..||||||||:||..|::||...
 Worm   504 LDCASQFLV-EAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNS 567

  Fly   628 EAQKIHITEEMHDSLQQ--VGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVR 677
            ...||.::|..|:.:::  .|.::.|.|..|::|....:.|:::..:.||.|
 Worm   568 SPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGPHR 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	58/342 (17%)
		HNOBA	<439..479	CDD:285003	15/39 (38%)
		CYCc	459..647	CDD:214485	90/199 (45%)
		Guanylate_cyc	485..669	CDD:278633	82/195 (42%)
gcy-31	NP_001024889.1	HNOB	2..164	CDD:285002	26/143 (18%)
		HNOBA	221..418	CDD:285003	47/223 (21%)
		CYCc	397..592	CDD:214485	91/203 (45%)
		Guanylate_cyc	429..613	CDD:278633	81/192 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920