Protein Alignment CG33958 and gcy-23

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_500309.3
• Gene: gcy-23 / 191652
• WormBaseID: WBGene00001548
• Length: 1073
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 166/524 - (31%)
• Similarity: 249/524 - (47%)
• Gaps: 95/524 - (18%)

  Fly   215 DDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEVMN--WYTSINRGLLHHLSEQIKETDNSGVW 277
            :::|.|:..::|.|| ...:|.:  ..:|.|:....:  :...|..||.:..|..|....:...|
 Worm   581 NEKEEMVVLWKFCSR-GTIQDMI--YNQEVSLDSKFHGAFIRDITLGLEYLHSSIIGYHGSLTPW 642

  Fly   278 RYLVGFKNLLKSIECQNIATSFGI-----RYYGRGSLTAENFVSYVRYEFMAREMINSTLNYAP- 336
            ..|:....::|       .|.:||     |:...|.::.|...........|::   ::|.|.|
 Worm   643 SCLIDRNWMIK-------LTDYGIANPLERWEKLGLISTETLKEGDDKSGSAQK---TSLLYQPP 697

  Fly   337 -MLKNMYTNITS------TKKFHRAKQMGTTL---------------LKNNPNVSNERSAIEYYE 379
             ||||..:|.|.      .|:....:|||...               ..|..|||         |
 Worm   698 EMLKNKESNRTRRMDQSWVKQSQARRQMGDIYAFGMVMHEILFRALPFPNGTNVS---------E 753

  Fly   380 LMNNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLI--------VSPVII---- 432
            :|:...|..:..:..:.       |:|.:..|         ||.:|:        |.|.|.
 Worm   754 VMDYIRDGTKTFRPTVH-------DRTQIHPD---------LVALLLDCWNENPEVRPSIRRVRL 802

  Fly   433 ----------VLVKNAAATIQLYALNLSQKAKE----LKREKRKSDSLLFQMLPPSVAMQLKQTQ 483
                      .||......::.||.||.:...|    |:....::|.||.|:||..||.:||..:
 Worm   803 NTENYLKVKGSLVDQMMRMMEQYANNLEKLVAERTGMLEEANVRADKLLGQLLPKYVANELKMGR 867

  Fly   484 QVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVA 548
            .|||:.::..|:.||||||||.|.:..||||||:.|||||..||:.|..:..||||||||:||:.
 Worm   868 SVPAKTFDMATVMFSDIVGFTTICSSSTPLEVVSMLNSIYSKFDDAINKHGSYKVETIGDAYMIV 932

  Fly   549 SGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLF 613
            ||:|.:|||:||..|...||:|:.....:.||...:..::||.|:|||.|.||:||...||||||
 Worm   933 SGIPEENGNEHIRNICNTALELMLLLKTYEIPHRRNVKLRIRLGIHTGTVAAGVVGLTAPRYCLF 997

  Fly   614 GDTVNTASRMESTGEAQKIHITEEMHD-SLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVR 677
            |||||.|||||||.|.:||.:::|..| .::....|:...||.::.||||.:::|||..|....:
 Worm   998 GDTVNVASRMESTSEPEKIQMSQEARDFCVRYYSEFQITLRGTVEAKGKGPVTSYWLLGKQSESQ 1062

  Fly   678 AREE 681
            .:::
 Worm  1063 MQQQ 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453	43/210 (20%)
		CYCc	459..647	CDD:214485	95/188 (51%)
gcy-23	NP_500309.3	PBP1_NPR_GC-like	30..407	CDD:380575
		PK_GC	509..806	CDD:270894	52/262 (20%)
		CYCc	842..1035	CDD:214485	96/192 (50%)