DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and gcy-9

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_509897.3	Gene:	gcy-9 / 191645	WormBaseID:	WBGene00001536	Length:	1081	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	114/249 - (45%)
Similarity:	152/249 - (61%)	Gaps:	11/249 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 LVKNAAATIQLYALNLSQKAKE----LKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVT 494
            ||......::.|..||....::    |:..::::|.||..|||.|:|..||..:.|..:||...|
Worm   834 LVDQMMKMMEEYTANLENMVRDRTALLEEAQKQADRLLNSMLPKSIAEDLKIGKPVLPQLYSCAT 898

  Fly   495 IYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKH 559
            :.||||.|||.|::..|||:||||||.::..||..|..:|.||||||||:||:.||:|.:|||.|
Worm   899 VLFSDIRGFTRISSTSTPLQVVTFLNDMFSGFDAIIAKHDAYKVETIGDAYMIVSGVPTENGNSH 963

  Fly   560 ISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRME 624
            ...||.:||.:......|::....:|.:.:|.|.|:|||.||:||...|||||||||||||||||
Worm   964 AQNIADVALKMRAFICNFKLAHRPEELMMVRIGFHSGPVAAGVVGLAAPRYCLFGDTVNTASRME 1028

  Fly   625 STGEAQKIHITEE----MHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDG 674
            |||.|.||.|:|.    :|....|   |:...||.|:|||||...||:|..:.|
Worm  1029 STGVANKIQISEGAYNLLHCFFPQ---FQMVERGKIEVKGKGECLTYYLEGRTG 1079

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	12/43 (28%)
		CYCc	459..647	CDD:214485	95/191 (50%)
		Guanylate_cyc	485..669	CDD:278633	96/187 (51%)
gcy-9	NP_509897.3	Periplasmic_Binding_Protein_Type_1	66..416	CDD:299141
		ANF_receptor	69..404	CDD:279440
		PKc_like	550..820	CDD:304357
		HNOBA	<837..883	CDD:285003	12/45 (27%)
		CYCc	862..1054	CDD:214485	95/194 (49%)
		Guanylate_cyc	889..1076	CDD:278633	97/189 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910