Protein Alignment CG33958 and gcy-3

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_496037.1
• Gene: gcy-3 / 191641
• WormBaseID: WBGene00001530
• Length: 1140
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 175/594 - (29%)
• Similarity: 264/594 - (44%)
• Gaps: 151/594 - (25%)

  Fly   219 MMLNRYEFQSRLN--------EFRDRVR---------LEPEESSITEVMNWYTSINRGLLHHLSE 266
            |:.||.|.|:|:|        :.|:..|         |:...|:||    ..:.::.|.....:.
 Worm   519 MIKNRREEQARINSEWQIPFVKLRELERKSKGTSKRSLQSAPSTIT----GESKVSTGSEFCENY 579

  Fly   267 QIKETDNSGVWRYLVGFKNL----------LKSIECQNIATSFGI-----------RYYGRGSLT 310
            ::|..:...|......:.||          |:.::.:|:....|:           :...||||.
 Worm   580 EVKMFEKDMVLTMKFQYMNLNKADMDKFVKLRKLDHENLNKFIGLSIDSSQFISVTKLCSRGSLL 644

  Fly   311 ----AENF-----------------VSYVRYEFMAREMINSTLNYAPMLKN-------------- 340
                ..||                 :||:...|:   .::..|..|..|.|
 Worm   645 DILYKGNFSMDFFFMYCIIKDVAEGMSYLHKSFL---RLHGNLRSATCLVNDSWQVKLAEFGFDQ 706

  Fly   341 MYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYE--------LMNNYTDDLRILQKALRR 397
            :...||.||:  |.......:|:.:..||....:.:.:.        |......||:      .|
 Worm   707 LLEEITPTKR--RLLWAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRKEAWDLK------ER 763

  Fly   398 LIKEYVDKTLVEADRKEAIGIA--ILVVVLIVSPVIIVLVKNAAA-------------------- 440
              ||..|:.:....:..:..|.  |:..|..|:|.:|.|||:..|
 Worm   764 --KEGYDEIIYRVKKGGSFPIRPDIITDVPDVNPTLIALVKDCWAEAPEDRPTAENICEQLRDLM 826

  Fly   441 -------------TIQLYA----LNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAE 488
                         .::.|.    :.:.::.|||..||:|:|.||.:|||..||.:||..|.|..|
 Worm   827 PKTKSNLMDHVFNMLEEYTSTLEVEVEERTKELTLEKKKADLLLSRMLPKQVAERLKAGQTVEPE 891

  Fly   489 LYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPV 553
            .:::||::|||:|.||.:|:.|||.:||..||.:|..||..||.:.|||||:|||.|:..||||.
 Worm   892 GFDSVTVFFSDVVKFTILASKCTPFQVVNLLNDLYSNFDTIIEEHGVYKVESIGDGYLCVSGLPT 956

  Fly   554 KNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVN 618
            :||..||.:|..|:|..:|....|:||....|.|::|.||::||.|||:||..||||||||||||
 Worm   957 RNGFNHIKQIVDMSLKFMDYCKNFKIPHLPRERVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVN 1021

  Fly   619 TASRMESTGEAQKIHITEEMHDSLQQ--VGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAREE 681
            |||||||.|:...||:|.:.|..|.:  ...:.|..||.:.:||||:|.|:|:..:.|
 Worm  1022 TASRMESNGKPSLIHLTSDAHLLLMKHFPHQYETNSRGEVIIKGKGVMETFWVLGRSG------- 1079

  Fly   682 ISWRADIQP 690
                 ||:|
 Worm  1080 -----DIEP 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	45/257 (18%)
		HNOBA	<439..479	CDD:285003	16/76 (21%)
		CYCc	459..647	CDD:214485	98/189 (52%)
		Guanylate_cyc	485..669	CDD:278633	93/185 (50%)
gcy-3	NP_496037.1	PBP1_NPR_GC_like	36..453	CDD:107347
		ANF_receptor	54..433	CDD:279440
		PKc_like	554..823	CDD:304357	50/285 (18%)
		HNOBA	<839..882	CDD:285003	15/42 (36%)
		CYCc	861..1051	CDD:214485	98/189 (52%)
		Guanylate_cyc	888..1076	CDD:278633	94/187 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910