Protein Alignment CG33958 and Npr1

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_032753.5
• Gene: Npr1 / 18160
• MGIID: 97371
• Length: 1057
• Species: Mus musculus
• Alignment Length: 559
• Identity: 186/559 - (33%)
• Similarity: 270/559 - (48%)
• Gaps: 136/559 - (24%)

  Fly   131 TLQEILEYRSAVADIETQVTIATDLGKVVTRLQLERSEVAFYIFTNGSKQRANLTL--RFA--NT 191
            :||:|||..|...|...:.::..|:.|.:  |.|....:.    ::|:.:.:|..:  ||.  .|
Mouse   615 SLQDILENESITLDWMFRYSLTNDIVKGM--LFLHNGAIG----SHGNLKSSNCVVDGRFVLKIT 673

  Fly   192 DHALNNMTTWSEISVPTAPDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEVMNWYTSI 256
            |:.|.:                                   |||.   |||:.........:|:.
Mouse   674 DYGLES-----------------------------------FRDP---EPEQGHTLFAKKLWTAP 700

  Fly   257 NRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRYYGRGSLTAENFVSYVRYE 321
            .  ||...|...:.:....|:.:         .|..|.||...|: :|..|
Mouse   701 E--LLRMASPPARGSQAGDVYSF---------GIILQEIALRSGV-FYVEG-------------- 739

  Fly   322 FMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYELMNN-YT 385
                      |:.:|  |.:...:|      |.:|.     ...|::..:....|..:||.. :.
Mouse   740 ----------LDLSP--KEIIERVT------RGEQP-----PFRPSMDLQSHLEELGQLMQRCWA 781

  Fly   386 DD------LRILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQL 444
            :|      .:.::.|||:..||....                            ::.|..:.::.
Mouse   782 EDPQERPPFQQIRLALRKFNKENSSN----------------------------ILDNLLSRMEQ 818

  Fly   445 YALNLSQKAKELKR----EKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTE 505
            ||.||.:..:|..:    ||||:::||:|:||.|||.|||:.:.|.||.:::||||||||||||.
Mouse   819 YANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTA 883

  Fly   506 IAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDL 570
            ::|:.||::|||.||.:|..||..|:.:||||||||||:|||.|||||:||..|..|:|.|||.|
Mouse   884 LSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALAL 948

  Fly   571 LDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHIT 635
            |||...|||.....|.:::|.|:|||||.||:||.||||||||||||||||||||.|||.:||::
Mouse   949 LDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHLS 1013

  Fly   636 EEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDG 674
            .|....|::..||..|.||.:::||||.:.||||..:.|
Mouse  1014 SETKAVLEEFDGFELELRGDVEMKGKGKVRTYWLLGERG 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	39/247 (16%)
		HNOBA	<439..479	CDD:285003	17/43 (40%)
		CYCc	459..647	CDD:214485	114/187 (61%)
		Guanylate_cyc	485..669	CDD:278633	110/183 (60%)
Npr1	NP_032753.5	PBP1_NPR_A	32..439	CDD:107380
		ANF_receptor	50..410	CDD:279440
		PK_GC-A_B	530..803	CDD:270944	50/280 (18%)
		TyrKc	543..797	CDD:197581	47/274 (17%)
		HNOBA	<812..857	CDD:285003	17/44 (39%)
		CYCc	836..1025	CDD:214485	114/188 (61%)
		Guanylate_cyc	863..1049	CDD:278633	112/185 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810