Protein Alignment CG33958 and gcy-33

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001256392.1
• Gene: gcy-33 / 179644
• WormBaseID: WBGene00001553
• Length: 947
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 145/586 - (24%)
• Similarity: 259/586 - (44%)
• Gaps: 127/586 - (21%)

  Fly   135 ILEYRSAVADIETQVTIATDLGKVVTRLQLERSEVAFYIFTNG-----SKQRANLTLRFANTDHA 194
            ||.|||......:.|     :|::|   :|.|   .||....|     .|::...|  |.....:
 Worm   130 ILHYRSRRTGYLSYV-----IGQLV---ELAR---VFYQLDIGIQVLKKKEKGRFT--FVVLKIS 181

  Fly   195 LNNMTTWSEISVPTAPDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEVMNWYTSINRG 259
            .:|:....::.:          :|.:.|       |||:     |..:..|..::..::.:.|:.
 Worm   182 FDNVGLGQDLKL----------KERVKN-------LNEY-----LPVDTKSFLQMFPFHIAFNKK 224

  Fly   260 LLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFG-----IRYYGRGSLTAENFVSYVR 319
            |...::.|              |..||:.:|:...:...|.     |::...|.:..:|.|..:.
 Worm   225 LEILMAGQ--------------GLLNLMPNIQGLLMTDVFDLQRPCIKFTAEGIMVHQNCVFQIE 275

  Fly   320 YEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYELMNN- 383
                         :..|::|....|||               ::.| :::.::.::|...:|:|
 Worm   276 -------------SLHPVVKQTEENIT---------------VQIN-DITEDKVSLEKKTVMDNE 311

  Fly   384 ----------YTDDLRILQKA-LRRLIKEYVDKTLVEADRKEAIGI------------AILVVVL 425
                      ....:.:|:.: ...|:...|..||   |....:|:            .|::..:
 Worm   312 YGLESLPYVTLRGPITVLKSSETFLLLATCVVDTL---DTMFKMGLYLNDFGESDCNREIIMATI 373

  Fly   426 IVSPVIIVLVKNAAATIQLYALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVP-AEL 489
            ..|..:..:::|.....::    |::..:|:...|:.:.:||.||:|..||..:.::..|. .|.
 Worm   374 QKSDTLKTMLENEKRRSEV----LTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGSVDHCEA 434

  Fly   490 YEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVK 554
            :|.|:|.|..:..|::|:......|||..||:||...|..::.:.||||||||:|||:::|.|.:
 Worm   435 FECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVYKVETIGESYMISAGCPYR 499

  Fly   555 NGNKHISEIATMALDLLDASSVFRIPRAGD--EFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTV 617
            : :.....::...|:::.....|.. ::.|  :.|.|:||:.|||||.|:||.:.||||||||||
 Worm   500 D-DYDAEMVSDCCLEMVSHIKSFEY-QSHDAVKKVLIKCGIFTGPVVGGVVGVRTPRYCLFGDTV 562

  Fly   618 NTASRMESTGEA-QKIHITEEMHDSL--QQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAR 679
            ||||||||:.:. ..|.|.:...|.:  |..|.||.:.:|.:.|||||.|..|.:..|.|..|.:
 Worm   563 NTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVKGKGDMRVYEIEKKKGRARYK 627

  Fly   680 E 680
            :
 Worm   628 K 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	39/258 (15%)
		HNOBA	<439..479	CDD:285003	10/39 (26%)
		CYCc	459..647	CDD:214485	74/193 (38%)
		Guanylate_cyc	485..669	CDD:278633	77/189 (41%)
gcy-33	NP_001256392.1	HNOB	2..164	CDD:377902	13/44 (30%)
		HNOBA	204..423	CDD:369471	43/268 (16%)
		CYCc	402..598	CDD:214485	76/197 (39%)
		COG5134	<595..744	CDD:227463	13/34 (38%)
		TDA11	<710..>898	CDD:293689

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920