Protein Alignment CG33958 and daf-11

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_505960.3
• Gene: daf-11 / 179605
• WormBaseID: WBGene00000907
• Length: 1077
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 161/606 - (26%)
• Similarity: 265/606 - (43%)
• Gaps: 117/606 - (19%)

  Fly   176 NGSKQRANLT--------LRFANTDHALNNMTTWSEISVPTAP-DEDEDDREMMLNRYEFQSRLN 231
            ||||.|:...        :||.:    |.|......:|:.:.. :.:|..|...|.|.:..:.::
 Worm   363 NGSKGRSISNPWVIPFQDVRFID----LTNTEGSQHMSIQSLQRNMEEKQRLQSLARTKHIATVD 423

  Fly   232 E---------FRDRVRLEPEESSIT---------EVMNWYTSIN---------------RGLLH- 262
            :         .||::|.:..:.::.         :.:|.:..|.               ||.||
 Worm   424 QVYVLADKYVMRDKLRYDKIDINLLYQMKSHLQHDNLNSFVGITIDKASHMYIIWNQCFRGSLHD 488

  Fly   263 HLSEQIKETDNSGVWRYLVGF-KNLLKSIE-CQNIATSFGIRYYGRGSLTAENFVSYVRY----- 320
            |:.  .||.......|:...| :::||.:| ....|..|      .|:||..|.:....:
 Worm   489 HIF--TKERQRGTATRFEGLFLRDILKGLEYIHASAIDF------HGNLTLHNCMLDSHWIVKLS 545

  Fly   321 EFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAI--EYYELMNN 383
            .|....::........:....:|.:..:::.|........:.||..: .|||:.|  ::.:..:.
 Worm   546 GFGVNRLLVKWKTSGQIFTEDHTPVIKSEELHYFDPAMKKIWKNYAD-RNERALITPQFGKKCDM 609

  Fly   384 YT-----DDLRILQKALRRLI---KEYVDKTLVEADRKEAI------------GI---------- 418
            |:     .::.:.:|.:.:|.   :|..|..|:: |..:||            ||
 Worm   610 YSFGVILHEIILKKKFVEQLFDSPREEDDSVLID-DENDAIASRFPLPIIIPEGIEMHNDLIKML 673

  Fly   419 ---------------AILVVVLIVSPVII-VLVKNAAATIQLYALNLSQKAKELKREKRKSDSLL 467
                           .|:..||.:|..:: :::||..|..|.....:..:..||::|:.|.|.||
 Worm   674 ENCFGSVRPDIALARKIIDTVLKMSGSLVDLMIKNLTAYTQGLNETVKNRTAELEKEQEKGDQLL 738

  Fly   468 FQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIEC 532
            .::||.|||..||....|..::||..||.:|||||||.:.:...|:||||.|:.:|:.||..|..
 Worm   739 MELLPKSVANDLKNGIAVDPKVYENATILYSDIVGFTSLCSQSQPMEVVTLLSGMYQRFDLIISQ 803

  Fly   533 YDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGP 597
            ...||:|||||:|.||:||||.....|:..|..:||...|....|.||.....|:..|.|.::||
 Worm   804 QGGYKMETIGDAYCVAAGLPVVMEKDHVKSICMIALLQRDCLHHFEIPHRPGTFLNCRWGFNSGP 868

  Fly   598 VVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQ-VGGFRTEHRGLIDVKGK 661
            |.||::|.|.|||..||:.|..||:|||:|...:|.:|......|:: ...|...:||...::|.
 Worm   869 VFAGVIGQKAPRYACFGEAVILASKMESSGVEDRIQMTLASQQLLEENFPQFVCSNRGGRTIEGI 933

  Fly   662 GLMSTYWLTCKDGPVRAREEI 682
            |.:.||||   :| |.|.|::
 Worm   934 GRILTYWL---EG-VNAGEQV 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453	48/276 (17%)
		CYCc	459..647	CDD:214485	81/188 (43%)
daf-11	NP_505960.3	Periplasmic_Binding_Protein_type1	2..289	CDD:471960
		Protein Kinases, catalytic domain	447..695	CDD:473864	41/257 (16%)
		CYCc	729..922	CDD:214485	82/192 (43%)