DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33958 and gcy-7

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_001360539.1	Gene:	gcy-7 / 179222	WormBaseID:	WBGene00001534	Length:	1117	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	128/247 - (51%)
Similarity:	171/247 - (69%)	Gaps:	5/247 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 IQLYALNL----SQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVG 502
            ::.||.:|    |::.|||..||:|||.||::|||.:||.:||..|.|..|.:|.|||:|||:|.
Worm   840 LESYASSLEEEVSERTKELVEEKKKSDVLLYRMLPKTVADKLKLGQTVEPETFEQVTIFFSDVVQ 904

  Fly   503 FTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMA 567
            ||.:|:.||||:||..||.:|.:||..||.:||||||||||.|:..||||.:|||:|:.:||.|:
Worm   905 FTTLASKCTPLQVVNLLNDLYTIFDGIIEKHDVYKVETIGDGYLCVSGLPHRNGNEHVRQIALMS 969

  Fly   568 LDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKI 632
            |..|.:...||:|....|.:.:|.|::.|.||||:||..|||:|||||.|||||||||.|:..||
Worm   970 LAFLSSLQFFRVPHLPSERINLRIGMNCGSVVAGVVGLTMPRFCLFGDAVNTASRMESNGKPGKI 1034

  Fly   633 HITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCK-DGPVRAREEIS 683
            |::.|.:..|..||||.||.||.:.:||||:|.|:|||.: .|.|.....:|
Worm  1035 HVSAEANRMLHLVGGFDTESRGEVIIKGKGVMETFWLTGQGTGAVSGARHVS 1086

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	19/40 (48%)
		CYCc	459..647	CDD:214485	102/187 (55%)
		Guanylate_cyc	485..669	CDD:278633	100/183 (55%)
gcy-7	NP_001360539.1	PBP1_NPR_GC-like	36..438	CDD:380575
		PKc_like	550..822	CDD:389743
		CYCc	860..1049	CDD:214485	102/188 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010