Protein Alignment CG33958 and acy-4

DIOPT Version :10

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_504486.4
• Gene: acy-4 / 178949
• WormBaseID: WBGene00000071
• Length: 1013
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 151/632 - (23%)
• Similarity: 259/632 - (40%)
• Gaps: 163/632 - (25%)

  Fly   149 VTIATDL------GKV----VTRLQLERSEVAFYIFTNGSKQRANLTLRFANTDHALNNMTTWSE 203
            ||:|..:      |:|    .||..|:.:    ||...|:   .....:|...:    .:.||
 Worm   422 VTLANQMESGGLAGRVHITDATRSYLKGA----YILEEGN---GGSRSKFLEKE----KIKTW-- 473

  Fly   204 ISVPTAPDEDEDDRE-----MML-----NRYEFQSRLNEFRDRVR-------LEPEESSITEVMN 251
            :.|..:||.|...:|     :|:     .....|.||.....|.|       |..||..:..|.:
 Worm   474 LVVDRSPDYDNICQEATNHPVMVPWKSTRGISKQERLTGMSTRTRGASTRNGLSEEEVLVENVDS 538

  Fly   252 WYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRYYGRGSLTAENFVS 316
                       ||.:.|:...... |          |::.|:|    :.::|   ..:..||...
 Worm   539 -----------HLRQGIQAIHQEN-W----------KTMHCKN----WSLKY---KQVRVENKFV 574

  Fly   317 YVRYE--------FMAREMINSTLNYAPM-------LKNMYTNITSTKKFHRAKQMGTTLLKNNP 366
            .::|:        ::|...|...:.:..|       :..|:..:||...|...:    .|:|:..
 Worm   575 RLKYKDIPFQVTLYVAIVAICIGIKFGLMNLVSFSFVPQMFIVLTSVMIFILTR----ALIKHAR 635

  Fly   367 NVSNERS------AIEYYELM----------------NNYTDDLRILQ----------------K 393
            .||....      :|:...||                |||||...|.:                |
 Worm   636 LVSLVIGVLFILLSIQIVILMGMYESKFTCDVEKCFKNNYTDFFEIFEICTLATCVILSVDFMTK 700

  Fly   394 ALRRLI-----KEYVDKTLVEADRKEAI--GIAILVVVLIVSPVIIVLVKNAAATIQLY----AL 447
            .|..:|     ...:...|:..::.||:  ..|...|:..::.:::|.....:..|..|    .|
 Worm   701 LLMSMIYFSSFTVLITAKLIRINQYEALLSTYANFCVLSCLTLLLVVFSTRRSELISRYDFIWKL 765

  Fly   448 NLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELY----EAVTIYFSDIVGFTEIAA 508
            ....:..::||:..::.|:|..:||..||....:.....::||    :...|.|:.:..|.:...
 Worm   766 QALDEQLQMKRKHEQNRSVLENILPSHVAKHFVEDATSVSKLYHESRDNACIMFATLTEFDKFYI 830

  Fly   509 DC----TPLEVVTFLNSIYRVFD-------ERIECYDVYKVETIGDSYMVASGLPVK--NGNKHI 560
            :|    ..:|.:..||.|...||       :|.|...:.|::||..:|||||||..:  ..|.|:
 Worm   831 ECDGNNEGVECLRLLNEIISDFDQILDQILDREEFKKIEKIKTISTTYMVASGLAGRECGDNSHV 895

  Fly   561 SEIATMALDL---LDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASR 622
            ..||..|.:|   |:::::    .:.:.| .:|.|::.||||||::|:..|.|.::|::||.|||
 Worm   896 EAIALFARELLVKLESTNI----HSFNNF-NLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASR 955

  Fly   623 MESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWL 669
            |:|.|.|.:|.:|||:...|:.: |:..|.||.|:|||||:|.|::|
 Worm   956 MDSGGVAGRIQVTEEVKSILEPL-GYNFECRGQINVKGKGMMETFFL 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:462453	56/306 (18%)
		CYCc	459..647	CDD:214485	64/207 (31%)
acy-4	NP_504486.4	AcyC	93..455	CDD:441717	10/36 (28%)
		Guanylate_cyc	293..448	CDD:425528	7/25 (28%)
		Guanylate_cyc	807..1003	CDD:425528	71/201 (35%)