DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and acy-1

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_497970.1	Gene:	acy-1 / 175622	WormBaseID:	WBGene00000068	Length:	1253	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	82/301 - (27%)
Similarity:	140/301 - (46%)	Gaps:	59/301 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 LSQKAKELKREKRKSDS------------LLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIV 501
            |.:.|.||:|....:||            .|.:|:|     :.::.:.....|...|:|.|:||.
Worm   267 LLKDASELRRPSASNDSNCRTSNATQVDQPLAKMVP-----EYRKFRPFTMNLMTNVSILFADIA 326

  Fly   502 GFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATM 566
            |||:::::.:..|:|..||.::..||.......:.|:.|:||.|...:|.| :..:.|......|
Worm   327 GFTKMSSNKSADELVNLLNDLFGRFDTLCRLRGLEKISTLGDCYYCVAGCP-EPCDDHACRTVEM 390

  Fly   567 ALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQK 631
            .||::.|...|.|.| |.| |.:|.|:|||.|:.|:||||..::.:|.:.|..|:.|||:|.|.:
Worm   391 GLDMIVAIRQFDIDR-GQE-VNMRVGIHTGKVMCGMVGTKRFKFDVFSNDVTLANEMESSGVAGR 453

  Fly   632 IHITE----------EMHDSLQQVGGFR-----TEHRGLIDVKGKGLMSTYWL--TCKDGPVRAR 679
            :|::|          |:.:.....|..|     ||.|    ||.:. |.|:::  ...||   ..
Worm   454 VHVSEATAKLLKGLYEIEEGPDYDGPLRMQVQGTERR----VKPES-MKTFFIKGRINDG---VE 510

  Fly   680 EEI--------------SWRADIQPVFLDHLKLHPPTDYKL 706
            ||:              |.::.::..:.:.||::....|.:
Worm   511 EEVMQVQEVESLHSQKSSKKSTLKQKWAEKLKMNHTNSYPM 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	10/41 (24%)
		CYCc	459..647	CDD:214485	60/209 (29%)
		Guanylate_cyc	485..669	CDD:278633	64/198 (32%)
acy-1	NP_497970.1	MreD	127..>223	CDD:294686
		CYCc	297..469	CDD:214485	57/179 (32%)
		Guanylate_cyc	317..503	CDD:278633	63/193 (33%)
		SDF	<773..982	CDD:294387
		CYCc	1016..1215	CDD:214485
		Guanylate_cyc	1041..1235	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810