Protein Alignment CG33958 and gcy-35

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001252131.1
• Gene: gcy-35 / 173202
• WormBaseID: WBGene00001555
• Length: 688
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 179/660 - (27%)
• Similarity: 294/660 - (44%)
• Gaps: 161/660 - (24%)

  Fly   157 KVVTRLQLE---RSEVAFYIFTNGSKQRANLTLRFANTDHALNNM-------------------- 198
            |:|...:.|   .||:|.|.  |..:     |||..|   ::.|:
 Worm    24 KIVHMSKFELGTESEIAHYY--NDDE-----TLRLVN---SMANVIGIPIEEIWEAYGGFLIQFT 78

  Fly   199 --TTWSEISVPTAPD-----EDEDDREMMLNRYEFQSRLN--EFRDRVRLEPEESSITEVMNWYT 254
              |.|.|:....|||     :..|.....::...::::|.  .||..|:.:.     |.::::|:
 Worm    79 METGWDELLRAMAPDLEGFLDSLDSLHYFIDHVVYKTKLRGPSFRCDVQADG-----TLLLHYYS 138

  Fly   255 S------INRGLLHHLSEQIKETD-------------NSGVWRYLVGFKNLLKSIECQN------ 294
            .      |.:|::..::.:|.:|:             ::.|..::|   .::..||..|
 Worm   139 KRSGLYPIVKGVVREVARRIYDTEVVMKVQERKQEHLDAFVTEHVV---FVITQIENANSTQPKS 200

  Fly   295 --------IATSFGIRYYGRGS----------------LTAENFVSYVRYEF---MARE-MINST 331
                    |..|.||  |...|                |..|:|.::::..|   |.:| .:...
 Worm   201 ISSKADSQIDLSTGI--YEISSSDFSLAFPYHICFDPDLFVEHFGNFIKKTFPNAMRQETRVTDL 263

  Fly   332 LNYA-PMLKNMYTNITSTKK---FHRAKQMG-----------TTLLKNNPNVSNERSAIEYYELM 381
            |... |.:...|.:|...|.   ..|.|.:|           |.|||.:....:|...|.|...:
 Worm   264 LELVHPEVPFSYESIKYYKNSLFVFRLKGLGDIVHNANDEAKTVLLKGSMVFIDEGKYILYMCSV 328

  Fly   382 NNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYA 446
            |..|             ::|.:::.|..:|.:...|... |::|..|.:..|.:..   |::...
 Worm   329 NVTT-------------VRELIERNLHLSDMQRHDGTRD-VIMLNQSRMSQVELNR---TLEETT 376

  Fly   447 LNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCT 511
            ..|.:.|:||:.||:|:|.||.:::|.|||..|:..:.:.|:.:...|:.|:|||.||.|.|.||
 Worm   377 KKLKKMAQELEIEKQKTDELLCELMPASVADSLRSGKAMDAKEFADCTLLFTDIVTFTNICAMCT 441

  Fly   512 PLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSV 576
            |.:|||.||.:|..||..:..:|.||||||||:||:..|:|.:..| |...:..:::.:|..|.:
 Worm   442 PYDVVTLLNDLYLRFDRLVGLHDAYKVETIGDAYMIVGGVPERCEN-HAERVLNISIGMLMESKL 505

  Fly   577 FRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDS 641
            ...| ...:.::||.|||.||||||:||.|||||||||||||.|::|||.|...|||::|
 Worm   506 VLSP-ITHKPIKIRLGVHCGPVVAGVVGIKMPRYCLFGDTVNVANKMESNGIQCKIHVSE----- 564

  Fly   642 LQQVGGFRTE------HRGLIDVKGKGLMSTYWLTCKDGPVRAREEISWRADIQP-----VFLDH 695
            ..::.|.:..      .||..:::|||:|.||:|...|     |:.: |....:|     ....:
 Worm   565 TGKLNGLKANPSYVFIDRGNTEIRGKGMMYTYFLERND-----RKSV-WELCSRPRSGEQTIDGY 623

  Fly   696 LKLHPPTDYK 705
            ::||..:.|:
 Worm   624 MELHDQSIYQ 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	63/336 (19%)
		HNOBA	<439..479	CDD:285003	15/39 (38%)
		CYCc	459..647	CDD:214485	85/187 (45%)
		Guanylate_cyc	485..669	CDD:278633	83/189 (44%)
gcy-35	NP_001252131.1	HNOB	3..167	CDD:285002	30/157 (19%)
		HNOBA	218..409	CDD:285003	47/207 (23%)
		CYCc	388..579	CDD:214485	86/197 (44%)
		Guanylate_cyc	415..599	CDD:278633	83/190 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920