Protein Alignment CG33958 and Gucy2c

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001120790.1
• Gene: Gucy2c / 14917
• MGIID: 106903
• Length: 1072
• Species: Mus musculus
• Alignment Length: 586
• Identity: 188/586 - (32%)
• Similarity: 255/586 - (43%)
• Gaps: 132/586 - (22%)

  Fly   182 ANLTLRFANTDHALNNMTTWSEI-SVPTAPDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESS 245
            |.|.||....|||| ....||.| |....|.|..:...:.|       ::::.|.|       .:
Mouse   450 ALLVLRKYRRDHAL-RQKKWSHIPSENIFPLETNETNHISL-------KIDDDRRR-------DT 499

  Fly   246 ITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFG---------- 300
            |..|........:.:|    :.:|.:|.:...:..:....||:| :..|:...:|
Mouse   500 IQRVRQCKYDKKKVIL----KDLKHSDGNFSEKQKIDLNKLLQS-DYYNLTKFYGTVKLDTRIFG 559

  Fly   301 -IRYYGRGSL--TAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLL 362
             :.|..||||  ...:.:||....||..|...|.||  .:.|.|       ...|.:|......|
Mouse   560 VVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLN--DIAKGM-------SYLHSSKIEVHGRL 615

  Fly   363 KNNPNVSNERSAIEYYELMNN-------------------------------------------- 383
            |:...|.:.|..::..:...|
Mouse   616 KSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQATISQKGDVYSFAIIAQEIILRKETF 680

  Fly   384 YTDDLRILQKALRRLIKEY-----VDKTLVEADRKEAIGIAILVVVLIV--------------SP 429
            ||...|...:.:.|:...|     .|..|..||.||      |.|.|:|              ..
Mouse   681 YTLSCRDHNEKIFRVENSYGKPFRPDLFLETADEKE------LEVYLLVKSCWEEDPEKRPDFKK 739

  Fly   430 VIIVLVK---------------NAAATIQLYALNLSQKAKE----LKREKRKSDSLLFQMLPPSV 475
            :...|.|               .....:|||:.||....:|    .|.|:.::|.|.|.:||..|
Mouse   740 IESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLV 804

  Fly   476 AMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVET 540
            ...||:...|..||||.||||||||||||.|....||:|||..||.||:.||:.::.:|||||||
Mouse   805 VKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVET 869

  Fly   541 IGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGT 605
            |||:|:||||||::|||:|..:|:.||||:|.....|.:.......|.||.|||:||..||:||.
Mouse   870 IGDAYVVASGLPMRNGNRHAVDISKMALDILSFIGTFELEHLPGLPVWIRIGVHSGPCAAGVVGI 934

  Fly   606 KMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVG-GFRTEHRGLIDVKGKGLMSTYWL 669
            ||||||||||||||||||||||...:||::......|::.. .|..|.||...:||:|..:||||
Mouse   935 KMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTITILKRTDCQFLYEVRGETYLKGRGTETTYWL 999

  Fly   670 T 670
            |
Mouse  1000 T 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	52/271 (19%)
		HNOBA	<439..479	CDD:285003	14/43 (33%)
		CYCc	459..647	CDD:214485	103/188 (55%)
		Guanylate_cyc	485..669	CDD:278633	103/184 (56%)
Gucy2c	NP_001120790.1	Periplasmic_Binding_Protein_Type_1	35..415	CDD:299141
		PKc_like	480..749	CDD:304357	53/302 (18%)
		STYKc	502..744	CDD:214568	46/261 (18%)
		CYCc	787..978	CDD:214485	103/190 (54%)
		Guanylate_cyc	814..1001	CDD:278633	106/187 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810