DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and Adcy7

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_006530643.1	Gene:	Adcy7 / 11513	MGIID:	102891	Length:	1146	Species:	Mus musculus

Alignment Length:	241	Identity:	84/241 - (34%)
Similarity:	131/241 - (54%)	Gaps:	29/241 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 KELKREKRKSDS-------LLFQMLPPSVAMQL---KQTQQVPAELYEAVTIYFSDI----VGFT 504
            |:.|:|..:.::       ||..:||..||...   |..:....:.|:.|.:.|:.:    |.:|
Mouse   848 KKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKAAEDWYHQSYDCVCVMFASVPDFKVFYT 912

  Fly   505 EIAADCTPLEVVTFLNSIYRVFDERI---ECYDVYKVETIGDSYMVASGLPVKNGNK-------- 558
            |...:...||.:..||.|...|||.:   :...|.|::|||.:||.|:||...:|::
Mouse   913 ECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSAPSGHENQDLERKH 977

  Fly   559 -HISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASR 622
             ||..:...::.|:  |.:..|.|......::|.|::.|||:||::|.:.|:|.::|:|||.|||
Mouse   978 VHIGVLVEFSMALM--SKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASR 1040

  Fly   623 MESTGEAQKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYW 668
            ||||||..||.:|||....||.: |:..|.||||:|||||.:.||:
Mouse  1041 MESTGELGKIQVTEETCTILQGL-GYSCECRGLINVKGKGELRTYF 1085

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	9/31 (29%)
		CYCc	459..647	CDD:214485	69/213 (32%)
		Guanylate_cyc	485..669	CDD:278633	74/200 (37%)
Adcy7	XP_006530643.1	AC_N	<75..251	CDD:318454
		Guanylate_cyc	272..422	CDD:306677
		DUF1053	487..593	CDD:399378
		Guanylate_cyc	890..1085	CDD:306677	73/197 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900