Protein Alignment CG33958 and gucy1b2

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_017949923.2
• Gene: gucy1b2 / 100496697
• XenbaseID: XB-GENE-989428
• Length: 781
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 169/580 - (29%)
• Similarity: 257/580 - (44%)
• Gaps: 148/580 - (25%)

  Fly   202 SEISVPTAPDEDEDDR----------------------------EMMLNRYEFQSRLNEFRDRVR 238
            :|||:......||::|                            ...:....|::..|::|||
 Frog   176 TEISMEIISQSDEEERTGKKEHIVFLVTQKPAFPPKCPTKPPLVSRGIKNKSFENPYNKYRDR-- 238

  Fly   239 LEPEESSITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIAT------ 297
              ..:.|:..|...:.::.||::           ..|..|.|.||:.:.....|.::.|
 Frog   239 --KNQVSVCPVKKNHWAMIRGIV-----------QLGKGRMLRGFRPVYPKDLCVDVETFCKGLP 290

  Fly   298 --------------------------SFGIR---YYG----RGSLTAENFVSYVRYEFM---ARE 326
                                      :.|||   |:.    ..:||..|...::..:|:   .||
 Frog   291 FHIVFDEELRIKQAGVSIQKIVPGLQTTGIRLDQYFSTVHPEVTLTISNVRKFINSQFVFRTKRE 355

  Fly   327 MINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYELMNNYTDDLRIL 391
            |:..:....|||:                            :..:...:|..|.|       ..|
 Frog   356 MMPESWRDRPMLE----------------------------LRGQMIWMEKLECM-------LYL 385

  Fly   392 QKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQK---- 452
            ...|.|.:.|..::.:..:|          :....|:..:|:|.:...|.::| :..|.:|
 Frog   386 CSPLLRTLHELEERQMHISD----------IAPHDVTRDLILLNQQRLAEMEL-SNQLERKKEEL 439

  Fly   453 ---AKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLE 514
               :|.|:.||:|::.||:.|||..||.|||:.::|.|..::..||.|||:|.||.|.|.|.|::
 Frog   440 RILSKHLEEEKKKTELLLYAMLPKHVANQLKEGKRVEAGEFKECTILFSDVVTFTNICAQCEPIQ 504

  Fly   515 VVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRI 579
            :|..|||:|..||.....:||||||||||:|||..|:||. .:.|...:|..||.::..:...:.
 Frog   505 IVFMLNSMYLRFDRLTTVHDVYKVETIGDAYMVVGGVPVP-VSSHAERVANFALGMILMAKQVKN 568

  Fly   580 PRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQ 644
            |..|:. :|||.|:|:|||:||:||.||||||||||||||||||||.|...||||:..::..|:.
 Frog   569 PVNGNP-IQIRVGLHSGPVLAGVVGEKMPRYCLFGDTVNTASRMESHGVPNKIHISPTVYRYLKG 632

  Fly   645 VGGFRTEHRGLIDVKGKGLMSTYWL----TCKDGPV---RAREEISWRADIQPVFLDHLK 697
             ..|....||.|||||||.|.||:|    :.|:..:   ..:|..|.||..|.:..|..|
 Frog   633 -KNFEMTERGEIDVKGKGRMRTYFLIRNSSAKENEILGQAIKETDSGRASSQSLLDDTSK 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	40/263 (15%)
		HNOBA	<439..479	CDD:285003	16/46 (35%)
		CYCc	459..647	CDD:214485	94/187 (50%)
		Guanylate_cyc	485..669	CDD:278633	94/183 (51%)
gucy1b2	XP_017949923.2	HNOB	21..182	CDD:400167	3/5 (60%)
		HNOBA	280..469	CDD:400168	42/234 (18%)
		Guanylate_cyc	475..657	CDD:306677	94/184 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920