Protein Alignment CG33958 and gucy1a1

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_002933521.3
• Gene: gucy1a1 / 100496677
• XenbaseID: XB-GENE-983418
• Length: 700
• Species: Xenopus tropicalis
• Alignment Length: 650
• Identity: 155/650 - (23%)
• Similarity: 262/650 - (40%)
• Gaps: 168/650 - (25%)

  Fly   166 RSEVAFYIFTNGSKQ-------RANLTLRFANTDHALNNMTTWSEIS---VPTAP---------- 210
            ||:|..:......::       |.||.|:.:...|.:...|:.|..|   :|:.|
 Frog    67 RSKVYLHTLAESIRKFIFPEFDRLNLALQRSIARHKIRGSTSRSAFSGFKLPSMPVCGKTAETEN 131

  Fly   211 ------------------------DE------DEDDREMMLNRYEFQSRLNEFRDRVRLEPEESS 245
                                    ||      :||:..:.:.....:..||.|...::...:..:
 Frog   132 FEKIVIDQSNAAGVPVEHVKETLGDELFRICYEEDEHVLQVVAGTLKDFLNSFGTHLKQSGQSRT 196

  Fly   246 ITEVMNWYTSINRGLLHHLSEQIKETDNSGVWRYLVGFKN---------LLKSIECQNIATSFGI 301
            :.|.    :.:..|.:..|.   |:.|...|:.:   |.|         ::::..|....|...:
 Frog   197 LEEC----SGLEEGSILCLE---KDQDYLNVYYF---FPNNITPLILPGIIRAAACILFETEVEV 251

  Fly   302 RYYGRGSLTAENFVS--YVRYEFMAREMINSTLNYAPMLKNMYTNITS-----TKKFHRAKQMGT 359
            |..........:|:.  |:.|....:   |:..:.:|.....|..|.:     |..||.......
 Frog   252 RLIPHSCSDGNDFIKEPYLLYSVQVK---NTRPSLSPSKPQSYVVIPASIFCKTFPFHFMFDKDM 313

  Fly   360 TLLK---------NNPNVSNERSAIEYYELMN-----NYTDDLRILQKALRRLIKEYVDKTLVEA 410
            |:|:         |..::..:.:..||:|:::     .::..|.:|.......:|.: |.|..:.
 Frog   314 TMLQIGNGVKRLLNWRDIPRKSTFEEYFEILSPKISCTFSGILTMLNMQFVIRVKTW-DSTTDQT 377

  Fly   411 DRKEAIGIAILVVVLIVSPVIIVL----------------------VKNAAATIQL--------- 444
            .:  |:.:...::.:..|..|:.|                      :.||...:.|
 Frog   378 SK--AMNLKGQMIYVFESSAILFLGSPCVDRLEDFTGQGLYLSDIPIHNALRDVVLTGEQARAQD 440

  Fly   445 --------YALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIV 501
                    ....|.|..:.|:.||:|:..|||.:.|..||.||.|.:.|.|:.:..||:.|||||
 Frog   441 GLKKRLGKLKATLEQAHQALEEEKKKTVDLLFSIFPGEVAQQLWQGETVQAKKFNNVTMLFSDIV 505

  Fly   502 GFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATM 566
            |||.|.:.|:|::|:|.|:.:|.:||.:....||||||||||:|.||.||. |....|..::|.|
 Frog   506 GFTAICSHCSPMQVITMLSELYTLFDFQCGELDVYKVETIGDAYCVAGGLH-KESETHAFQVALM 569

  Fly   567 ALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQK 631
            ||.:::.|.....|..  |.:::|.|:|:|.||||:||.:||||||||:.|..|::.||....:|
 Frog   570 ALKMMELSDEVMSPHG--EQIKMRIGLHSGSVVAGVVGVRMPRYCLFGNNVTLANKFESCSVPRK 632

  Fly   632 IHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCKDGPVRAREEISWRADIQPVFLDHL 696
            |:::.             |.:|.|.|.||      :..|.:.           |.|:.|.|..|:
 Frog   633 INVSP-------------TTYRLLKDYKG------FTFTPRS-----------RQDLPPNFPSHI 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	49/309 (16%)
		HNOBA	<439..479	CDD:285003	13/56 (23%)
		CYCc	459..647	CDD:214485	81/187 (43%)
		Guanylate_cyc	485..669	CDD:278633	75/183 (41%)
gucy1a1	XP_002933521.3	HNOBA	294..483	CDD:400168	34/191 (18%)
		Guanylate_cyc	489..676	CDD:306677	81/211 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920