DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and adcy1

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_002933461.1	Gene:	adcy1 / 100492373	XenbaseID:	XB-GENE-950909	Length:	1122	Species:	Xenopus tropicalis

Alignment Length:	306	Identity:	93/306 - (30%)
Similarity:	155/306 - (50%)	Gaps:	52/306 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 IAILVVVLI------------------VSPVIIVLVKNAAATIQ------------LYALNLSQK 452
            :.||.:|::                  ..|::.:|:.:.:..:.            |:|:...::
Frog   749 VTILYIVILEISGYRKTLGGDTSYMRGYEPILAILLFSCSLALHSRQVDLKLRLDYLWAVQAEEE 813

  Fly   453 AKELKREKRKSDSLLFQMLPPSVA----MQLKQTQQVPAELYEAVTIYFSDIVGFT----EIAAD 509
            ..:::|.|..:..:||.:||..||    |...:...:..:.|..|.:.|:.|..|.    |:..:
Frog   814 RDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGN 878

  Fly   510 CTPLEVVTFLNSIYRVFDERI--ECY-DVYKVETIGDSYMVASGLPVKNGNK-------HISEIA 564
            ...:|.:..||.|...|||.:  ||| |:.|::|||.:||.|.||....|.|       |:|.:|
Frog   879 NMGVECLRLLNEIIADFDELMEKECYKDIEKIKTIGSTYMGAVGLVPTTGTKAKKSIYSHLSTLA 943

  Fly   565 TMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEA 629
            ..::::.|....... ::.:||| :|.|::.||||||::|.:.|:|.::|:|||.||||:|||..
Frog   944 DFSIEMFDVLDEINY-QSYNEFV-LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ 1006

  Fly   630 QKIHITEEMHDSLQQVGGFRTEHRGLIDVKGKGLMSTYWLTCK-DG 674
            .||.:||::|..|:.. .:....||.:.|||||.|.||:|..| ||
Frog  1007 GKIQVTEDVHRILKSC-NYEFVCRGKVSVKGKGEMLTYFLEGKIDG 1051

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	11/55 (20%)
		CYCc	459..647	CDD:214485	71/205 (35%)
		Guanylate_cyc	485..669	CDD:278633	73/197 (37%)
adcy1	XP_002933461.1	AC_N	<37..282	CDD:292831
		CYCc	248..443	CDD:214485
		Guanylate_cyc	284..466	CDD:278633
		CYCc	817..1028	CDD:214485	72/213 (34%)
		Guanylate_cyc	850..1047	CDD:278633	74/199 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910