DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33958 and gucy1a2

DIOPT Version :9

Sequence 1:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_009290254.2	Gene:	gucy1a2 / 100330875	ZFINID:	ZDB-GENE-121023-3	Length:	608	Species:	Danio rerio

Alignment Length:	200	Identity:	82/200 - (41%)
Similarity:	123/200 - (61%)	Gaps:	3/200 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 LSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPL 513
            |.:..:.|:.|||::..||:.:.|..||.:|.|...|.|:.::.||:.||||||||.:.|.|||:
Zfish   351 LEKTHQALEEEKRRTVDLLYSIFPGDVAQRLWQGLPVQAKKFDDVTMLFSDIVGFTAVCAQCTPM 415

  Fly   514 EVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFR 578
            :|::.||.:|..||.:....||||:|||||:|.||.||..|. :.|...||.|||.:::.|....
Zfish   416 QVISMLNELYTRFDYQCGILDVYKIETIGDAYCVAGGLHRKI-DSHAKPIALMALKMMELSEEVL 479

  Fly   579 IPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQ 643
            .|  ..:.:::|.|:|:|.|:||:||..||||||||:.|..||:.||....:.|:::...:..|:
Zfish   480 TP--DGKPIKLRIGIHSGSVLAGVVGVMMPRYCLFGNNVTLASKFESGSHPRCINVSPTTYQLLR 542

  Fly   644 QVGGF 648
            ....|
Zfish   543 DDRSF 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	10/29 (34%)
		CYCc	459..647	CDD:214485	79/187 (42%)
		Guanylate_cyc	485..669	CDD:278633	69/163 (42%)
gucy1a2	XP_009290254.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820