Protein Alignment CG33958 and gucy1b1

DIOPT Version :9

• Sequence 1: NP_001033958.1
• Gene: CG33958 / 37088
• FlyBaseID: FBgn0053958
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001238874.1
• Gene: gucy1b1 / 100150304
• ZFINID: ZDB-GENE-090313-160
• Length: 608
• Species: Danio rerio
• Alignment Length: 577
• Identity: 159/577 - (27%)
• Similarity: 245/577 - (42%)
• Gaps: 149/577 - (25%)

  Fly   135 ILEY---RSAVADIETQV--TIATDLG------KVVTRLQLERSEVAFYIFTNGSKQRANLTLRF 188
            ||.|   |..:.||...:  |:|..:.      ||:.....|...:.|.|....|::.|    .:
Zfish   132 ILHYYSEREGLQDIVIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEA----FY 192

  Fly   189 ANTDHALNNMTTWSEISVPT----APDEDEDDREMMLNRYEFQSRLNEFRDRVRLEPEESSITEV 249
            .:.|....|.|..:.||..|    .|.....|:::||.    |.....||...:|:|...:::.|
Zfish   193 EDLDGFEENGTQETRISPYTFCKAFPFHLMFDKDLMLT----QCGNAIFRVLPQLQPGVCNLSSV 253

  Fly   250 MNWYTSINR--------GLLHHLSEQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRYYGR 306
            .    |:.|        |:|.|::..           :::..|..|.::|
Zfish   254 F----SLVRPHIDFSFHGILSHINTV-----------FVLRSKEGLLNVE--------------- 288

  Fly   307 GSLTAENFVSYVRYEFMAREMINSTLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSN- 370
               ||||           .:.:..|......||....::..|:..         |...:|:|.|
Zfish   289 ---TAEN-----------EDELTGTEISCLRLKGQMISLPETENI---------LFLCSPSVMNL 330

  Fly   371 ---ERSAIEYYEL-MNNYTDDLRILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVI 431
               .|..:...:: :::.|.||.:|.:..|   :||
Zfish   331 DDLTRRGLYLSDIPLHDATRDLVLLGEQFR---EEY----------------------------- 363

  Fly   432 IVLVKNAAATIQLYALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIY 496
                 .....:::....|....:.|:.||:|:|.||:.:||||||.:|:..:.|||:.|:.|||.
Zfish   364 -----KLTQELEILTDRLQHTLRALEDEKKKTDRLLYSVLPPSVANELRHKRPVPAKRYDNVTIL 423

  Fly   497 FSDIVGFTEIAADCT-------PLEVVTFLNSIYRVF----DERIECYDVYKVETIGDSYMVASG 550
            ||.||||.   |.|:       .:::|..||.||..|    |.|...| ||||||:||.||..||
Zfish   424 FSGIVGFN---AFCSKHASAEGAIKIVNLLNDIYTRFDILTDSRKNPY-VYKVETVGDKYMTVSG 484

  Fly   551 LPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGD 615
            || :....|...|..:|||:::.:...::   .::.|||..|:|||.||.|::|.:||||||||:
Zfish   485 LP-EPCTHHAKSICHLALDMMEIAGQVKV---DEDPVQITIGIHTGEVVTGVIGQRMPRYCLFGN 545

  Fly   616 TVNTASRMESTGEAQKIHITEEMHDSLQQVGG----FRTEHRGLIDVKGKGLMSTYW 668
            |||..||.|:|||..||:::|..:..||.|..    |..|:||.:.:|||......|
Zfish   546 TVNLTSRTETTGEKGKINVSEYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVW 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	46/253 (18%)
		HNOBA	<439..479	CDD:285003	14/39 (36%)
		CYCc	459..647	CDD:214485	90/198 (45%)
		Guanylate_cyc	485..669	CDD:278633	85/199 (43%)
gucy1b1	NP_001238874.1	HNOB	2..166	CDD:285002	8/33 (24%)
		HNOBA	207..406	CDD:285003	55/292 (19%)
		CYCc	385..584	CDD:214485	91/206 (44%)
		Guanylate_cyc	412..605	CDD:278633	85/199 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820