DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10916 and CG5506

DIOPT Version :9

Sequence 1:	NP_001261070.1	Gene:	CG10916 / 37081	FlyBaseID:	FBgn0034312	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_649021.1	Gene:	CG5506 / 39992	FlyBaseID:	FBgn0036766	Length:	180	Species:	Drosophila melanogaster

Alignment Length:	162	Identity:	49/162 - (30%)
Similarity:	72/162 - (44%)	Gaps:	16/162 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VPIDLDRDSLPDA----HLPPEGAVQCGTNEDGLPTYVARGYYHDDLLPAPYVPEKKAA-FGSHS 167
            ||...|.:.:..|    ::.|..||..|.:..|..|||.|..|.:.:|||..|.|...| |.:.:
  Fly    18 VPSTYDTEHVWKAGNLSYVIPYNAVVGGFDPYGFTTYVGRVKYSNSILPARVVAETGTAYFNTET 82

  Fly   168 CSARTLTDDVEILVLNDCDYKWVPGQHGTYPRDALNTGYSELGEVTY-----TGRGLYQGILRLG 227
            .|::.|..|: ::...|.:|.||....|.|.:.|:..|.:...|..:     |..|:..|.|.|.
  Fly    83 TSSKLLVYDI-LVAERDVNYVWVRSFDGFYEKGAVAVGTTVKNERVFCCRAKTDGGILIGTLLLS 146

  Fly   228 KVHPSHKVMYIPHHGQEV-SVNTYEVLVVTPR 258
                |.||..|.|....: ..:.|||||..|:
  Fly   147 ----SQKVCIIKHESLALRKFDKYEVLVAQPK 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10916	NP_001261070.1	zf-RING_2	32..74	CDD:290367
		zf-rbx1	<32..74	CDD:289448
		DM9	105..183	CDD:128937	24/79 (30%)
		DUF3421	133..246	CDD:288732	35/119 (29%)
		DM9	186..254	CDD:128937	21/73 (29%)
CG5506	NP_649021.1	DM9	25..96	CDD:128937	21/71 (30%)
		DUF3421	47..161	CDD:288732	35/118 (30%)
		DM9	100..172	CDD:128937	23/75 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005929
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940