Protein Alignment Dgp-1 and gtpbp2

DIOPT Version :10

• Sequence 1: NP_611302.1
• Gene: Dgp-1 / 37080
• FlyBaseID: FBgn0027836
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001072714.1
• Gene: gtpbp2 / 780171
• XenbaseID: XB-GENE-996416
• Length: 584
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 265/584 - (45%)
• Similarity: 375/584 - (64%)
• Gaps: 39/584 - (6%)

  Fly     8 PNGVAVGVGI--------------KSARSNIFNVDGLPQQMAAMSVDYSSIRGKDVLVQPTEEQI 58
            |.|.:.|.|.              :|::||  |...||.:....:::|     |..||.|::.:.
 Frog    11 PAGGSGGTGARGKTKGKKAGKGRGRSSKSN--NPPYLPPEAEEGNIEY-----KLKLVNPSQYRF 68

  Fly    59 ELLQKRLQDRIADNCGETIYEIGVGEDGSDSGLNPEQFEASVATLHLLAANIDADVVKLRERRAE 123
            |.|..:::.|:.:..||.:|:|||.::|...||:.|:.:||:.|||.:|..:.||:..||||..:
 Frog    69 EHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMKASLHTLHRMAEKVGADITVLREREVD 133

  Fly   124 KGQSA-----QFLIRKHIDTTDFMEIRVAVVGNVDAGKSTLLGVLTHGELDNGRGHARQRLFRHK 183
            ....:     :.||||..|...|:::||||:||||:||||||||||.||||||||.||..||||.
 Frog   134 YDSDSPRKITEVLIRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHL 198

  Fly   184 HEIESGRTSSVGNDILGFDGVGNVVNKPDHGHLDWVKICENSAKVITFIDLAGHERYLKTTVFGM 248
            |||:||||||:..:||||:..|.|:|..:....:  :|||:::|:|||||||||.:|||||:||:
 Frog   199 HEIQSGRTSSISFEILGFNSKGEVINYSESRTAE--QICESASKMITFIDLAGHHKYLKTTIFGL 261

  Fly   249 TGHAPDFGMLMIGANAGIIGMTKEHLGLALALAVPVFVVVTKIDMCPANVLQENMKLLFKMLKSQ 313
            |.:.|||.||::.||.||.|.|:||||||:||.||.|:||:|:|:|.|..::..::.|.:.||..
 Frog   262 TSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFLVVSKVDLCAAATVERTLRQLERTLKQP 326

  Fly   314 GCRKVPVVVRSHDDVVLSATNFV-SERLCPIFQVSNVTGDNLELLKMFLNLLSTRMPGSE----- 372
            ||.|||.:|||.||.|.:|..|. |..:.|||.:|:|||::|:|||:|||:|.......|
 Frog   327 GCNKVPFMVRSEDDAVTAAQQFAQSPNITPIFAISSVTGESLDLLKVFLNILPPLTNSHEQEELM 391

  Fly   373 -SLPAEFQIDDVYAVPGVGTVVSGTCLQGTIRLNDCLMLGPDAVGSFVPITIKSIHRKRMNVARV 436
             .|| |||:|::|.||.|||||.||...|..:..:.|::||...|.|:|:.:.||.|.|.....:
 Frog   392 QQLP-EFQVDEIYTVPEVGTVVGGTLYSGVCKEGEHLVVGPTDGGGFLPLKVCSIQRNRSTCRVL 455

  Fly   437 RCGQTASFALKKIKRAYLRKGMVMVSQDLKPQACWEFEGEILVLHHPTTISARYQAMVHCGSIRQ 501
            |.||.|:.||.:.:|:.||||||:||.:..|..||.||.||::|.|.|:.....|..||.|::||
 Frog   456 RAGQAATLALGEFERSLLRKGMVLVSPEALPTVCWVFEAEIVLLFHATSCRQGVQVTVHVGNVRQ 520

  Fly   502 TASIIHM-SRDCLRTGDKAHVKFRFIKQPEYIRAGQRLVFREGRTKAVGNI--LRPLPNAAASP 562
            ||.:.|: .:|.||||:||.|:|||||.|||::.|.:|:||||.||.:|::  |:.:..|...|
 Frog   521 TAVLEHIHGKDELRTGEKAVVRFRFIKHPEYLKPGTKLLFREGMTKGIGHVCSLQVIATAIGDP 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgp-1	NP_611302.1	GTPBP1	55..556	CDD:444076	248/515 (48%)
		dermokine	<561..>651	CDD:455732	1/2 (50%)
gtpbp2	NP_001072714.1	GTPBP1_like	160..380	CDD:206728	129/221 (58%)
		GTPBP_II	395..481	CDD:293895	39/86 (45%)
		GTPBP_III	487..574	CDD:294007	43/86 (50%)