Protein Alignment Dgp-1 and gtpbp1

DIOPT Version :10

• Sequence 1: NP_611302.1
• Gene: Dgp-1 / 37080
• FlyBaseID: FBgn0027836
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001072172.1
• Gene: gtpbp1 / 594925
• XenbaseID: XB-GENE-951182
• Length: 666
• Species: Xenopus tropicalis
• Alignment Length: 636
• Identity: 393/636 - (61%)
• Similarity: 469/636 - (73%)
• Gaps: 32/636 - (5%)

  Fly    26 NVDGLPQQMAAMSVDYSSIRGKDVLVQPTEEQIELLQKRLQDRIADNCGETIYEIGVGEDGSDSG 90
            ::||.|.:.....:|.:|   |.|||.|:.||.:.|.::|:||:.:..|||||.||.|.||::.|
 Frog    35 SLDGEPLRNGEADIDLTS---KLVLVSPSAEQYDSLLRQLRDRMDEGRGETIYVIGQGSDGTEYG 96

  Fly    91 LNPEQFEASVATLHLLAANIDADVVKLRERRAEKGQSAQFLIRKHIDTTDFMEIRVAVVGNVDAG 155
            ||....||||||:..:|..|.||::.|||.:...|:...:|:||.:...||:|:|||||||||||
 Frog    97 LNEADMEASVATVTSMAEQIIADMILLREHQEAGGKVRDYLVRKSVGDNDFLEVRVAVVGNVDAG 161

  Fly   156 KSTLLGVLTHGELDNGRGHARQRLFRHKHEIESGRTSSVGNDILGFDGVGNVVNKPDH--GHLDW 218
            ||||||||||||||||||.|||:||||||||||||||||||||||||..|.||||||.  |.|:|
 Frog   162 KSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSHGQVVNKPDSHGGSLEW 226

  Fly   219 VKICENSAKVITFIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGIIGMTKEHLGLALALAVP 283
            .||||.|:|:||||||||||:||||||||||||.|||.|||:|:||||:|||||||||||||.||
 Frog   227 TKICEKSSKIITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVP 291

  Fly   284 VFVVVTKIDMCPANVLQENMKLLFKMLKSQGCRKVPVVVRSHDDVVLSATNFVSERLCPIFQVSN 348
            ||||||||||||||:|||.:|||.::|||.||||:||:|::.|||:::|:||.|||:|||||:||
 Frog   292 VFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQNKDDVIVTASNFSSERMCPIFQISN 356

  Fly   349 VTGDNLELLKMFLNLLSTRMPGSESLPAEFQIDDVYAVPGVGTVVSGTCLQGTIRLNDCLMLGPD 413
            |||:|:|||||||||||.|....|..||||||||.|:|||||||||||.|:|.|:|||.|:||||
 Frog   357 VTGENMELLKMFLNLLSPRSSSREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDLLLLGPD 421

  Fly   414 AVGSFVPITIKSIHRKRMNVARVRCGQTASFALKKIKRAYLRKGMVMVSQDLKPQACWEFEGEIL 478
            .:|:|..|.:||||||||.|..||.|||||||||||||:.:||||||||..|.|||.||||.|||
 Frog   422 PLGNFTSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEIL 486

  Fly   479 VLHHPTTISARYQAMVHCGSIRQTASIIHMSRDCLRTGDKAHVKFRFIKQPEYIRAGQRLVFREG 543
            |||||||||.|||||||||||||||:|:.||||||||||||.|.|||||.|||:...||||||||
 Frog   487 VLHHPTTISPRYQAMVHCGSIRQTATILSMSRDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREG 551

  Fly   544 RTKAVGNILRPLPNAAASPYRPKPAKMQSRSHNGGSNGSNNQH-----------RQQGQGSSSGA 597
            ||||||.|.:.|.:....|...||.:::.:|.....:|..::.           .....|.::||
 Frog   552 RTKAVGTITKLLQSTNNLPMNSKPQQVKMQSTKKSPHGKKDEQIPGAAVPEEASPSAAVGVTAGA 616

  Fly   598 G-------------CSKDNADEKQNGDKREGGSRRGGKRKRNNRPT-PSGG 634
            |             |..:|..:...|.:|.||.|.  |.|.....| |:||
 Frog   617 GSLQAQTASAEDFQCRAENKPKTGGGGRRRGGQRH--KVKSQGACTAPTGG 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgp-1	NP_611302.1	GTPBP1	55..556	CDD:444076	360/502 (72%)
		dermokine	<561..>651	CDD:455732	22/99 (22%)
gtpbp1	NP_001072172.1	GTPBP1	66..563	CDD:444076	358/496 (72%)
		GTPBP1_like	151..375	CDD:206728	181/223 (81%)