DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Naus and Filip1l

DIOPT Version :9

Sequence 1:	NP_001286565.1	Gene:	Naus / 37076	FlyBaseID:	FBgn0034308	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_001035487.2	Gene:	Filip1l / 78749	MGIID:	1925999	Length:	1131	Species:	Mus musculus

Alignment Length:	352	Identity:	95/352 - (26%)
Similarity:	174/352 - (49%)	Gaps:	30/352 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TENCSGSGMSVGDTVSANHEFQ---------TMKPGPGVVHK-VMPVANSASSATATNGRTRSEM 79
            :.|..||...   .:..:.:||         |.|..|....: |:|...|..|.|. .|....::
Mouse     5 SSNAEGSAPK---QIPRHSKFQDSIQDMKHRTHKKDPSCESEGVLPRPVSEKSHTG-KGHHTEDL 65

  Fly    80 PHSELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLIS 144
            ...:|:.:|..|||||||||..|..||.|::...:.:.:...:.|.....|:.||
Mouse    66 SRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEALQRD---------- 120

  Fly   145 RESSTQAAQAEMEVRQIIEQQMEQQYQMVSKQRATHVRMVNILTESLENNQRMLQELEEEKRKHE 209
               :.||..|..: ..|.|:.|.:..::|.|.:.:|.|::..|.....::::.:.|:|||||||:
Mouse   121 ---AFQAKSAPWQ-EDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHK 181

  Fly   210 NTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYERNRQKQIVLLLIAERKK 274
            ....:.|:....||.|..:||:.:::|.|...|.|::.:|..:||:.|..:.|...|:::.|:::
Mouse   182 EYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQR 246

  Fly   275 ILMKYIEEGKRSEDLAQILAEEKQRSDTIAEG-LEEESKKSLRMEEELEKQTHAMEQERKVLFAK 338
            :..:...:.::.:.|. ..|:|.|....:||. .:||.:|:.|:|:||:.||....|.:..:.||
Mouse   247 LTAQLALQRQKIQALT-TSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAK 310

  Fly   339 LAKEELRVKELEQELNALRSEHEALKK 365
            |..|:.:.::|.|:|.||..:.:.|::
Mouse   311 LTNEDSQNRQLRQKLAALSRQIDELEE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_001286565.1	CortBP2	78..274	CDD:286770	55/195 (28%)
Naus	NP_001286565.1	Angiomotin_C	189..381	CDD:289044	51/178 (29%)
Filip1l	NP_001035487.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		14/60 (23%)
		CortBP2	64..246	CDD:286770	55/195 (28%)
		Laminin_II	291..>377	CDD:283628	15/47 (32%)
		COG1340	325..598	CDD:224259	4/13 (31%)
		PARM	906..>1128	CDD:293666
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1103
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910